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	<title>Comments on: CDC:  &#8220;Thank you, Sallie, May We Have Another?&#8221;</title>
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	<description>Autism news and opinion</description>
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		<title>By: A bad day for antivaccinationists: Yet another study fails to support an association between vaccines and neurodevelopmental disorders : Left Brain/Right Brain</title>
		<link>http://leftbrainrightbrain.co.uk/2007/09/cdc-thank-you-sallie-may-we-have-another/#comment-44753</link>
		<dc:creator>A bad day for antivaccinationists: Yet another study fails to support an association between vaccines and neurodevelopmental disorders : Left Brain/Right Brain</dc:creator>
		<pubDate>Sun, 30 Sep 2007 18:10:47 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=655#comment-44753</guid>
		<description>[...] CDC: &quot;Thank you, Sallie, May We Have Another?&quot; &#187; (31) Schwartz, Joseph, More Evidence for the Safety of Vaccines : Left Brain/Right Brain, Schwartz, Joseph, Kev [...] [...]</description>
		<content:encoded><![CDATA[<p>[...] <span class="caps">CDC</span>: &#8220;Thank you, Sallie, May We Have Another?&#8221; &raquo; (31) Schwartz, Joseph, More Evidence for the Safety of Vaccines : Left Brain/Right Brain, Schwartz, Joseph, Kev [...] [...]</p>
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		<title>By: Schwartz</title>
		<link>http://leftbrainrightbrain.co.uk/2007/09/cdc-thank-you-sallie-may-we-have-another/#comment-44736</link>
		<dc:creator>Schwartz</dc:creator>
		<pubDate>Sun, 30 Sep 2007 06:49:00 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=655#comment-44736</guid>
		<description>Joseph

I agree that the conclusion was accurate to the letter of the text.  But that&#039;s easy to accomplish and still mislead people.  

I do feel it underplayed the weaknesses and combined with the press release, it overreached it&#039;s implications.  

The study authors should have known better IMO.  But as far as bias goes, it is no where near other stuff I&#039;ve read.  We&#039;ll see what happens to Sallie.</description>
		<content:encoded><![CDATA[<p>Joseph</p>
<p>I agree that the conclusion was accurate to the letter of the text.  But that&#8217;s easy to accomplish and still mislead people.</p>
<p>I do feel it underplayed the weaknesses and combined with the press release, it overreached it&#8217;s implications.</p>
<p>The study authors should have known better <span class="caps">IMO</span>.  But as far as bias goes, it is no where near other stuff I&#8217;ve read.  We&#8217;ll see what happens to Sallie.</p>
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		<title>By: Joseph</title>
		<link>http://leftbrainrightbrain.co.uk/2007/09/cdc-thank-you-sallie-may-we-have-another/#comment-44705</link>
		<dc:creator>Joseph</dc:creator>
		<pubDate>Sat, 29 Sep 2007 19:22:32 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=655#comment-44705</guid>
		<description>The last sentence of what I said was unrelated to anything else, yeah. (I still think it would be a good idea though.) But I stand by my position that Sallie Bernard has absolutely no excuse to have dissented, would not have dissented if the results had been different, and that the conclusion is exactly what it should&#039;ve been. I&#039;m sure it was a very well though out conclusion. Note that it doesn&#039;t say anything has been disproved. It simply states that the study does not support a causal association. It does not, in any way shape or form. Theoretical confounds and such are noted in the paper. They even explain quite well why the recruitment was what it was, and most importantly, they note that exposure distribution was similar in the selected group compared to the entire sample. This is a key indication that there was no selection bias.</description>
		<content:encoded><![CDATA[<p>The last sentence of what I said was unrelated to anything else, yeah. (I still think it would be a good idea though.) But I stand by my position that Sallie Bernard has absolutely no excuse to have dissented, would not have dissented if the results had been different, and that the conclusion is exactly what it should&#8217;ve been. I&#8217;m sure it was a very well though out conclusion. Note that it doesn&#8217;t say anything has been disproved. It simply states that the study does not support a causal association. It does not, in any way shape or form. Theoretical confounds and such are noted in the paper. They even explain quite well why the recruitment was what it was, and most importantly, they note that exposure distribution was similar in the selected group compared to the entire sample. This is a key indication that there was no selection bias.</p>
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		<title>By: More Evidence for the Safety of Vaccines : Left Brain/Right Brain</title>
		<link>http://leftbrainrightbrain.co.uk/2007/09/cdc-thank-you-sallie-may-we-have-another/#comment-44702</link>
		<dc:creator>More Evidence for the Safety of Vaccines : Left Brain/Right Brain</dc:creator>
		<pubDate>Sat, 29 Sep 2007 18:57:46 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=655#comment-44702</guid>
		<description>[...] CDC: &quot;Thank you, Sallie, May We Have Another?&quot; &#187; (28) Schwartz, Joseph, Kev, Schwartz, Schwartz, isles [...] [...]</description>
		<content:encoded><![CDATA[<p>[...] <span class="caps">CDC</span>: &#8220;Thank you, Sallie, May We Have Another?&#8221; &raquo; (28) Schwartz, Joseph, Kev, Schwartz, Schwartz, isles [...] [...]</p>
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		<title>By: Schwartz</title>
		<link>http://leftbrainrightbrain.co.uk/2007/09/cdc-thank-you-sallie-may-we-have-another/#comment-44700</link>
		<dc:creator>Schwartz</dc:creator>
		<pubDate>Sat, 29 Sep 2007 18:17:48 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=655#comment-44700</guid>
		<description>Kev,

Unlike Isles, a blogger from another site has actually provided more specific information (Interverbal) obtained personally that the dissent was not registered until the end of the trial.  Given that knowledge, I support any criticism leveled at Sally regarding the study design as she had the opportunity to comment on it. 

However, I don&#039;t see how you can blame someone for dissenting on the basis of the Concluding dialog since that would not have been known until the end.  Again, a number of her criticisms revolve around the wording of the conclusions, and some of those are valid IMO.

As for this:  &quot;b) that peer review doesn’t equate to a better standard of science&quot;

When will you stop using peer review to justify the results of a study?  Do we need to review all the studies of the peer review process so see that it does not guarantee good science?  I&#039;m not advocating that peer review be scrapped because I think it&#039;s a good thing as far as process is concerned.  I also think it needs to be overhauled to make it more effective.  However, when analyzing details of SPECIFIC studies and cases, the peer review is irrelevent as evidence in support of the conclusions if only because the process itself was not published or available for public review.  That&#039;s pretty fundamental.

Joseph,

You&#039;re one of the most articulate/accurate posters here, so I am surprised at the vehemence.  I come to this site to gather and understand logical well presented arguments in the Autism-Vaccination debate as well as learning more about Autism itself.

I originally got hooked into the debate many years ago, not because of Autism, but because I was doing research to help me decide whether and how to vaccinate my own children.  These days, the debate mostly centers around autism (has plusses and minus&#039;) so that is why I&#039;m here. 

What does not aid debate, are allegations, conjecture and questions of conspiracy without providing real data or even first hand personal information.  The sad part is that commentary like this article tend to totally distract from some beneficial discussion of the study itself (which the author assumed was 100 correct and accurate based on peer-review mind you).  

Why not discuss the actual merits of the study because all the information is available and published for us to discuss?

Since only a few people actually know the sequence of events, personal communications, the rest of us can only guess at the sequence of events and make allegations.

What I can confidently say right now, is that any comments from Sallie about the study design is not justified given she reviewed the design (unless it was modified after the review -- but I have nothing to suggest that it was).

I personally find the concluding statements to be farther reaching than the evidence provided in the study.  There is no earlier time to dissent to the concluding statements until after they are written.

&quot;The Omnibus hearings should be dismissed with prejudice.&quot;

This I find a bit shocking.  Why do you feel that no one has the right to have their case heard in a scientific hearing as they are entitled to by the system and the law?  And remember, if you want to win that argument, you need to provide specifics, because every case is different.  From what I read of the first hearing there was more than enough evidence in the Cedillo case to justify a hearing.  (PLEASE NOTE:  I didn&#039;t say find in favour of, just to justify a hearing)</description>
		<content:encoded><![CDATA[<p>Kev,</p>
<p>Unlike Isles, a blogger from another site has actually provided more specific information (Interverbal) obtained personally that the dissent was not registered until the end of the trial.  Given that knowledge, I support any criticism leveled at Sally regarding the study design as she had the opportunity to comment on it.</p>
<p>However, I don&#8217;t see how you can blame someone for dissenting on the basis of the Concluding dialog since that would not have been known until the end.  Again, a number of her criticisms revolve around the wording of the conclusions, and some of those are valid <span class="caps">IMO</span>.</p>
<p>As for this:  &#8220;b) that peer review doesn&#8217;t equate to a better standard of science&#8221;</p>
<p>When will you stop using peer review to justify the results of a study?  Do we need to review all the studies of the peer review process so see that it does not guarantee good science?  I&#8217;m not advocating that peer review be scrapped because I think it&#8217;s a good thing as far as process is concerned.  I also think it needs to be overhauled to make it more effective.  However, when analyzing details of <span class="caps">SPECIFIC</span> studies and cases, the peer review is irrelevent as evidence in support of the conclusions if only because the process itself was not published or available for public review.  That&#8217;s pretty fundamental.</p>
<p>Joseph,</p>
<p>You&#8217;re one of the most articulate/accurate posters here, so I am surprised at the vehemence.  I come to this site to gather and understand logical well presented arguments in the Autism-Vaccination debate as well as learning more about Autism itself.</p>
<p>I originally got hooked into the debate many years ago, not because of Autism, but because I was doing research to help me decide whether and how to vaccinate my own children.  These days, the debate mostly centers around autism (has plusses and minus&#8217;) so that is why I&#8217;m here.</p>
<p>What does not aid debate, are allegations, conjecture and questions of conspiracy without providing real data or even first hand personal information.  The sad part is that commentary like this article tend to totally distract from some beneficial discussion of the study itself (which the author assumed was 100 correct and accurate based on peer-review mind you).</p>
<p>Why not discuss the actual merits of the study because all the information is available and published for us to discuss?</p>
<p>Since only a few people actually know the sequence of events, personal communications, the rest of us can only guess at the sequence of events and make allegations.</p>
<p>What I can confidently say right now, is that any comments from Sallie about the study design is not justified given she reviewed the design (unless it was modified after the review&#8212;but I have nothing to suggest that it was).</p>
<p>I personally find the concluding statements to be farther reaching than the evidence provided in the study.  There is no earlier time to dissent to the concluding statements until after they are written.</p>
<p>&#8220;The Omnibus hearings should be dismissed with prejudice.&#8221;</p>
<p>This I find a bit shocking.  Why do you feel that no one has the right to have their case heard in a scientific hearing as they are entitled to by the system and the law?  And remember, if you want to win that argument, you need to provide specifics, because every case is different.  From what I read of the first hearing there was more than enough evidence in the Cedillo case to justify a hearing.  (PLEASE <span class="caps">NOTE</span>:  I didn&#8217;t say find in favour of, just to justify a hearing)</p>
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		<title>By: Joseph</title>
		<link>http://leftbrainrightbrain.co.uk/2007/09/cdc-thank-you-sallie-may-we-have-another/#comment-44689</link>
		<dc:creator>Joseph</dc:creator>
		<pubDate>Sat, 29 Sep 2007 13:54:59 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=655#comment-44689</guid>
		<description>I don&#039;t think Sallie Bernard has an reasonable excuse for this. If she does, let&#039;s hear it. What did she think the conclusions of the study should say? That expected random fluctuations might be actual effects? That theoretical and unlikely confounds (known before the results) invalidate the study altogether?

Obviously, the only reason she dissented is that she didn&#039;t like the results.

Are we to believe that if the results had shown an actual risk effect, she would&#039;ve dissented because of potential confounds? Come on.

At this point, SafeMinds is no longer SafeMinds. It&#039;s ClosedMinds. I&#039;d normally try to be polite in these discussions, but in this case things have gone far enough, and I can only conclude SafeMinds is composed of a bunch of closed-minded assholes. The CDC should not even give the time of day from now on. Let them talk among themselves on EOHarm. The Omnibus hearings should be dismissed with prejudice.</description>
		<content:encoded><![CDATA[<p>I don&#8217;t think Sallie Bernard has an reasonable excuse for this. If she does, let&#8217;s hear it. What did she think the conclusions of the study should say? That expected random fluctuations might be actual effects? That theoretical and unlikely confounds (known before the results) invalidate the study altogether?</p>
<p>Obviously, the only reason she dissented is that she didn&#8217;t like the results.</p>
<p>Are we to believe that if the results had shown an actual risk effect, she would&#8217;ve dissented because of potential confounds? Come on.</p>
<p>At this point, SafeMinds is no longer SafeMinds. It&#8217;s ClosedMinds. I&#8217;d normally try to be polite in these discussions, but in this case things have gone far enough, and I can only conclude SafeMinds is composed of a bunch of closed-minded assholes. The <span class="caps">CDC</span> should not even give the time of day from now on. Let them talk among themselves on EOHarm. The Omnibus hearings should be dismissed with prejudice.</p>
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		<title>By: Kev</title>
		<link>http://leftbrainrightbrain.co.uk/2007/09/cdc-thank-you-sallie-may-we-have-another/#comment-44671</link>
		<dc:creator>Kev</dc:creator>
		<pubDate>Sat, 29 Sep 2007 06:15:57 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=655#comment-44671</guid>
		<description>Schwartz, I&#039;m sorry, I appreciate your desire to be plausible but you&#039;re not.

If you seriously believe that:

a) Sally Bernard wouldn&#039;t have hollered about the terrible study before now

or

b) that peer review doesn&#039;t equate to a better standard of science

then I can only conclude that you&#039;ve been smoking crack.

Being sceptical is one thing. Being sceptical to the point of unreality is just being silly.</description>
		<content:encoded><![CDATA[<p>Schwartz, I&#8217;m sorry, I appreciate your desire to be plausible but you&#8217;re not.</p>
<p>If you seriously believe that:</p>
<p>a) Sally Bernard wouldn&#8217;t have hollered about the terrible study before now</p>
<p>or</p>
<p>b) that peer review doesn&#8217;t equate to a better standard of science</p>
<p>then I can only conclude that you&#8217;ve been smoking crack.</p>
<p>Being sceptical is one thing. Being sceptical to the point of unreality is just being silly.</p>
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		<title>By: Schwartz</title>
		<link>http://leftbrainrightbrain.co.uk/2007/09/cdc-thank-you-sallie-may-we-have-another/#comment-44669</link>
		<dc:creator>Schwartz</dc:creator>
		<pubDate>Sat, 29 Sep 2007 05:35:39 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=655#comment-44669</guid>
		<description>&quot;Sallie versus a host of scientists does not invite a referendum on the value of the peer review process.&quot;

You are absolutely correct.  This statement does:  &quot;The issue is that Sallie, a non-scientist, is raising a hue and cry over a paper that dozens of actual scientists signed off on; some from CDC, some external.&quot;

Again, supporting an argument about a published study based on who wrote it is pretty pointless.  Why not argue the specifics of the issues raised?  I think I know the answer.</description>
		<content:encoded><![CDATA[<p>&#8220;Sallie versus a host of scientists does not invite a referendum on the value of the peer review process.&#8221;</p>
<p>You are absolutely correct.  This statement does:  &#8220;The issue is that Sallie, a non-scientist, is raising a hue and cry over a paper that dozens of actual scientists signed off on; some from <span class="caps">CDC</span>, some external.&#8221;</p>
<p>Again, supporting an argument about a published study based on who wrote it is pretty pointless.  Why not argue the specifics of the issues raised?  I think I know the answer.</p>
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		<title>By: Schwartz</title>
		<link>http://leftbrainrightbrain.co.uk/2007/09/cdc-thank-you-sallie-may-we-have-another/#comment-44668</link>
		<dc:creator>Schwartz</dc:creator>
		<pubDate>Sat, 29 Sep 2007 05:30:38 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=655#comment-44668</guid>
		<description>Isles,

Too bad you can&#039;t tell who is saying those words.  You still have a bunch of unsubstantiated allegations.  You don&#039;t know what information was provided to her.  You don&#039;t know what information she provided in return.  You also don&#039;t know when she expressed her dissenting opinion.

Who is the one smearing here?</description>
		<content:encoded><![CDATA[<p>Isles,</p>
<p>Too bad you can&#8217;t tell who is saying those words.  You still have a bunch of unsubstantiated allegations.  You don&#8217;t know what information was provided to her.  You don&#8217;t know what information she provided in return.  You also don&#8217;t know when she expressed her dissenting opinion.</p>
<p>Who is the one smearing here?</p>
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		<title>By: isles</title>
		<link>http://leftbrainrightbrain.co.uk/2007/09/cdc-thank-you-sallie-may-we-have-another/#comment-44663</link>
		<dc:creator>isles</dc:creator>
		<pubDate>Sat, 29 Sep 2007 03:13:37 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=655#comment-44663</guid>
		<description>http://www.nytimes.com/2007/09/27/health/27vaccine.html?_r=1

&quot;Ms. Bernard served on a board of consultants that helped design and oversee the study, but she withdrew her support for the published version of the study, saying its conclusions were not supported by the underlying data.&quot;

Sallie versus a host of scientists does not invite a referendum on the value of the peer review process.  It invites rotten tomatoes directed at Ms. Bernard, who deserves every last splat.</description>
		<content:encoded><![CDATA[<p><a href="http://www.nytimes.com/2007/09/27/health/27vaccine.html?_r=1" rel="nofollow">http://www.nytimes.com/2007/09......html?_r=1</a></p>
<p>&#8220;Ms. Bernard served on a board of consultants that helped design and oversee the study, but she withdrew her support for the published version of the study, saying its conclusions were not supported by the underlying data.&#8221;</p>
<p>Sallie versus a host of scientists does not invite a referendum on the value of the peer review process.  It invites rotten tomatoes directed at Ms. Bernard, who deserves every last splat.</p>
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