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	<title>Comments on: Autism Omnibus and shrinking hypotheses</title>
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	<link>http://leftbrainrightbrain.co.uk/2008/05/autism-omnibus-and-shrinking-hypotheses/</link>
	<description>Autism news and opinion</description>
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		<title>By: Autism Blog - AAP and Paul Offit under attack (again) &#124; Left Brain/Right Brain</title>
		<link>http://leftbrainrightbrain.co.uk/2008/05/autism-omnibus-and-shrinking-hypotheses/#comment-51668</link>
		<dc:creator>Autism Blog - AAP and Paul Offit under attack (again) &#124; Left Brain/Right Brain</dc:creator>
		<pubDate>Mon, 07 Jul 2008 12:22:44 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=820#comment-51668</guid>
		<description>[...] first line appearance and see the multitude of times your predictions have been wrong, that your hypotheses have failed and the threats of violence that you make to those who oppose [...]</description>
		<content:encoded><![CDATA[<p>[...] first line appearance and see the multitude of times your predictions have been wrong, that your hypotheses have failed and the threats of violence that you make to those who oppose [...]</p>
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		<title>By: The Regression Question</title>
		<link>http://leftbrainrightbrain.co.uk/2008/05/autism-omnibus-and-shrinking-hypotheses/#comment-51032</link>
		<dc:creator>The Regression Question</dc:creator>
		<pubDate>Mon, 16 Jun 2008 07:44:50 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=820#comment-51032</guid>
		<description>[...] regressive autism&#8221; has been key. &#8220;Clearly regressive autism&#8221; is described in an expert report by Dr. Sander Greenland, a professor of epidemiology at the UCLA School of Public Health and [...]</description>
		<content:encoded><![CDATA[<p>[...] regressive autism&#8221; has been key. &#8220;Clearly regressive autism&#8221; is described in an expert report by Dr. Sander Greenland, a professor of epidemiology at the <span class="caps">UCLA </span>School of Public Health and [...]</p>
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		<title>By: Regressive Autism and a Test for Babies</title>
		<link>http://leftbrainrightbrain.co.uk/2008/05/autism-omnibus-and-shrinking-hypotheses/#comment-50055</link>
		<dc:creator>Regressive Autism and a Test for Babies</dc:creator>
		<pubDate>Fri, 16 May 2008 06:13:16 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=820#comment-50055</guid>
		<description>[...] UCLA College of Letters and Science. From reading Prof. Greenland&#8217;s expert report (go to this post and scroll down to see a PDF file of the submitted report), Kev notes in Petitioners suggest new [...]</description>
		<content:encoded><![CDATA[<p>[...] <span class="caps">UCLA </span>College of Letters and Science. From reading Prof. Greenland&#8217;s expert report (go to this post and scroll down to see a <span class="caps">PDF</span> file of the submitted report), Kev notes in Petitioners suggest new [...]</p>
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		<title>By: Ms. Clark</title>
		<link>http://leftbrainrightbrain.co.uk/2008/05/autism-omnibus-and-shrinking-hypotheses/#comment-50016</link>
		<dc:creator>Ms. Clark</dc:creator>
		<pubDate>Wed, 14 May 2008 21:36:51 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=820#comment-50016</guid>
		<description>Speaking of &quot;sympthatic&quot; and parents.  The father of one of the test cases testified today.  It was Mr. Mead.  He is divorced from  the boy&#039;s mother.  This guy gave a pretty good description of William  having a plateau of development (not adding new words but adding a &quot;verbal stim&quot;) some time after he was a year old and then some time around 18 months (if I remember correctly) he had a more obvious regression, where he was losing his balance and stopped speaking (or mostly stopped).  The dad puts this down to his having two vaccines 6 or 8 weeks apart.  The second of those two, though didn&#039;t show up on William&#039;s vaccine records or in his medical records from the sound of it.  

He was sickly from 3 months of age on and had &quot;bronchiolitis&quot; and lots of ear infections.  

&lt;b&gt;What was most interesting to me is to see how rapidly the parents descended into the abyss of autism quackery.&lt;/b&gt;  Before he was diagnosed with autism, but after he was referred to an autism clinic for a diagnosis (by an audiologist), they put the boy on the GFCF diet and he immediately felt better.  He had been having &quot;explosive diarrhea&quot; and he was very thin, even though he was eating alot.  But the GFCF diet didn&#039;t help William be less autistic, except for the eye contact and some other minor issues were resolved.  So the mom went to the OASIS conference in Oregon and hear Dr. Green speak (top DAN! doc, been disciplined by the Oregon State Medical board for putting stuff into a kid with IV that later send the kid to an ER where the mom couldn&#039;t tell the docs what had been put into the kid).  And then they were off and running into biomed.

They ended up seeing Green who did his usual battery of tests, including having parents send provoked urine samples to a mail order lab (Doctor Green uses DDI labs, for his provoked urine heavy metals, so maybe the Meads sent the urine there).  

Mr. Mead was utterly shocked to find out that his son&#039;s provoked (note: provoked with a chelator) urine sample was &lt;b&gt;a shocking &quot;7 times the reference level&quot;&lt;/b&gt;.  Apparently, Mr. Mead wasn&#039;t told or didn&#039;t notice the note at the bottom of the lab test that says, they are using norms are for unprovoked urine samples.  So yeah, getting a &quot;high&quot; level of mercury dumped from the kid&#039;s kidneys&#039; where &quot;high&quot; is compared to non-provoked urine samples is scary for the uninitiated parents, as it is expected to be, one would assume.

The kid got oral DMSA (which caused yeast to flare up... dad knows this from reading on the Internet), he got IV DMPS, and EDTA (dad then hastened to add that it was &quot;calcium edta&quot;).  He got TD-dmsa and TD-glutathione.

And one very traumatic session of IVIG.  After which they said they&#039;d never do that again.  I don&#039;t know when they did the IV chelation because the dad described the process of putting an IV into his son as &quot;horrific&quot;.  His word.  

Time Buie scoped the boy and they found lymphoid hyperplasia.  Buie suspected a problem with the boy&#039;s pancreas and they found that he was missing some pancreatic enzymes and some other enzymes (might explain all that diarrhea, I think).  He had 2 or three doses of secretin.  He&#039;s been on low-dose naltrexone and the atkins diet. They bought supplements from Green as well as from other sources. 

The dad and mom apparently at one point were thinking it was measles from the MMR because they gave him &quot;vitamin A&quot; for that (a ridiculous quack therapy).  I guess it was the boys high level of mercury in that first test that really got them on to thimerosal.  

Dad made a point of saying that his son had 7 times the reference range of &quot;the second most toxic substance on the planet after plutonium.&quot;  He said it like he was horrified.  

I couldn&#039;t believe my ears.  I wonder if the PSC expected him to say that.   It&#039;s classic DAN!-world sciencey-talk.</description>
		<content:encoded><![CDATA[<p>Speaking of &#8220;sympthatic&#8221; and parents.  The father of one of the test cases testified today.  It was Mr. Mead.  He is divorced from  the boy&#8217;s mother.  This guy gave a pretty good description of William  having a plateau of development (not adding new words but adding a &#8220;verbal stim&#8221;) some time after he was a year old and then some time around 18 months (if I remember correctly) he had a more obvious regression, where he was losing his balance and stopped speaking (or mostly stopped).  The dad puts this down to his having two vaccines 6 or 8 weeks apart.  The second of those two, though didn&#8217;t show up on William&#8217;s vaccine records or in his medical records from the sound of it.</p>
<p>He was sickly from 3 months of age on and had &#8220;bronchiolitis&#8221; and lots of ear infections.</p>
<p><b>What was most interesting to me is to see how rapidly the parents descended into the abyss of autism quackery.</b>  Before he was diagnosed with autism, but after he was referred to an autism clinic for a diagnosis (by an audiologist), they put the boy on the <span class="caps">GFCF</span> diet and he immediately felt better.  He had been having &#8220;explosive diarrhea&#8221; and he was very thin, even though he was eating alot.  But the <span class="caps">GFCF</span> diet didn&#8217;t help William be less autistic, except for the eye contact and some other minor issues were resolved.  So the mom went to the <span class="caps">OASIS</span> conference in Oregon and hear Dr. Green speak (top <span class="caps">DAN</span>! doc, been disciplined by the Oregon State Medical board for putting stuff into a kid with IV that later send the kid to an ER where the mom couldn&#8217;t tell the docs what had been put into the kid).  And then they were off and running into biomed.</p>
<p>They ended up seeing Green who did his usual battery of tests, including having parents send provoked urine samples to a mail order lab (Doctor Green uses <span class="caps">DDI</span> labs, for his provoked urine heavy metals, so maybe the Meads sent the urine there).</p>
<p>Mr. Mead was utterly shocked to find out that his son&#8217;s provoked (note: provoked with a chelator) urine sample was <b>a shocking &#8220;7 times the reference level&#8221;</b>.  Apparently, Mr. Mead wasn&#8217;t told or didn&#8217;t notice the note at the bottom of the lab test that says, they are using norms are for unprovoked urine samples.  So yeah, getting a &#8220;high&#8221; level of mercury dumped from the kid&#8217;s kidneys&#8217; where &#8220;high&#8221; is compared to non-provoked urine samples is scary for the uninitiated parents, as it is expected to be, one would assume.</p>
<p>The kid got oral <span class="caps">DMSA </span>(which caused yeast to flare up&#8230; dad knows this from reading on the Internet), he got <span class="caps">IV DMPS</span>, and <span class="caps">EDTA </span>(dad then hastened to add that it was &#8220;calcium edta&#8221;).  He got TD-dmsa and TD-glutathione.</p>
<p>And one very traumatic session of <span class="caps">IVIG</span>.  After which they said they&#8217;d never do that again.  I don&#8217;t know when they did the IV chelation because the dad described the process of putting an IV into his son as &#8220;horrific&#8221;.  His word.</p>
<p>Time Buie scoped the boy and they found lymphoid hyperplasia.  Buie suspected a problem with the boy&#8217;s pancreas and they found that he was missing some pancreatic enzymes and some other enzymes (might explain all that diarrhea, I think).  He had 2 or three doses of secretin.  He&#8217;s been on low-dose naltrexone and the atkins diet. They bought supplements from Green as well as from other sources.</p>
<p>The dad and mom apparently at one point were thinking it was measles from the <span class="caps">MMR</span> because they gave him &#8220;vitamin A&#8221; for that (a ridiculous quack therapy).  I guess it was the boys high level of mercury in that first test that really got them on to thimerosal.</p>
<p>Dad made a point of saying that his son had 7 times the reference range of &#8220;the second most toxic substance on the planet after plutonium.&#8221;  He said it like he was horrified.</p>
<p>I couldn&#8217;t believe my ears.  I wonder if the <span class="caps">PSC</span> expected him to say that.   It&#8217;s classic <span class="caps">DAN</span>!-world sciencey-talk.</p>
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		<title>By: Sullivan</title>
		<link>http://leftbrainrightbrain.co.uk/2008/05/autism-omnibus-and-shrinking-hypotheses/#comment-50009</link>
		<dc:creator>Sullivan</dc:creator>
		<pubDate>Wed, 14 May 2008 19:47:04 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=820#comment-50009</guid>
		<description>They don&#039;t have to prove the group exists.  If they can present a &#039;plausible&#039; description of how they might exist, then it is in the HHS/DOJ&#039;s hands to refute it.

Given that the vaccine/autism group is now &quot;below the radar&quot;, it becomes more difficult.

It was a good move for them in this case, as it removes one of the strong arguments against the old theory (that autism is an epidemic of vaccine injury).

If this is successful, even for a small number in the Omnibus, they can then take the rest to Civil court with the description that &quot;vaccine induced autism is possible&quot;, something they can&#039;t say now.

If anyone thinks that this is just speculation--well, it is.  It was speculated by Mr. Kirby almost a year ago:

&lt;blockquote&gt;But if even one case of causation is determined, then private lawsuits in civil courts -- where the drug makers themselves are on trial -- would soon flood the dockets. (Ironically, if families lose in Vaccine Court, they are free to sue in civil court. Having autistic kids appear before sympathetic juries is Big Pharma&#039;s big nightmare, and it&#039;s why a secret rider was attached to the Homeland Security Act of 2002 to bar thimerosal cases from civil court and force them into Vaccine Court).&lt;/blockquote&gt;</description>
		<content:encoded><![CDATA[<p>They don&#8217;t have to prove the group exists.  If they can present a &#8216;plausible&#8217; description of how they might exist, then it is in the <span class="caps">HHS</span>/DOJ&#8217;s hands to refute it.</p>
<p>Given that the vaccine/autism group is now &#8220;below the radar&#8221;, it becomes more difficult.</p>
<p>It was a good move for them in this case, as it removes one of the strong arguments against the old theory (that autism is an epidemic of vaccine injury).</p>
<p>If this is successful, even for a small number in the Omnibus, they can then take the rest to Civil court with the description that &#8220;vaccine induced autism is possible&#8221;, something they can&#8217;t say now.</p>
<p>If anyone thinks that this is just speculation&#8212;well, it is.  It was speculated by Mr. Kirby almost a year ago:</p>
<p>
<blockquote>But if even one case of causation is determined, then private lawsuits in civil courts&#8212;where the drug makers themselves are on trial&#8212;would soon flood the dockets. (Ironically, if families lose in Vaccine Court, they are free to sue in civil court. Having autistic kids appear before sympathetic juries is Big Pharma&#8217;s big nightmare, and it&#8217;s why a secret rider was attached to the Homeland Security Act of 2002 to bar thimerosal cases from civil court and force them into Vaccine Court).</p></blockquote>
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		<title>By: Ms. Clark</title>
		<link>http://leftbrainrightbrain.co.uk/2008/05/autism-omnibus-and-shrinking-hypotheses/#comment-50008</link>
		<dc:creator>Ms. Clark</dc:creator>
		<pubDate>Wed, 14 May 2008 19:19:20 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=820#comment-50008</guid>
		<description>This hypothetical tiny group that is too small to find with epidemiology reminds me of Bertrand Russell&#039;s quote that is on Brian Deer&#039;s website.

&quot;If I were to suggest that between the Earth and Mars there is a china teapot revolving about the sun in an elliptical orbit, nobody would be able to disprove my assertion provided I were careful to add that the teapot is too small to be revealed even by our most powerful telescopes.&quot;</description>
		<content:encoded><![CDATA[<p>This hypothetical tiny group that is too small to find with epidemiology reminds me of Bertrand Russell&#8217;s quote that is on Brian Deer&#8217;s website.</p>
<p>&#8220;If I were to suggest that between the Earth and Mars there is a china teapot revolving about the sun in an elliptical orbit, nobody would be able to disprove my assertion provided I were careful to add that the teapot is too small to be revealed even by our most powerful telescopes.&#8221; </p>
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		<title>By: _Arthur</title>
		<link>http://leftbrainrightbrain.co.uk/2008/05/autism-omnibus-and-shrinking-hypotheses/#comment-50005</link>
		<dc:creator>_Arthur</dc:creator>
		<pubDate>Wed, 14 May 2008 16:13:29 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=820#comment-50005</guid>
		<description>Right.  They have no evidence that their hypothetical subgroup exist, they have no evidence that this subgroup correspond to their clients, they have no causal evidence linking  the &quot;damage&quot; to vaccines, except generally fuzzy temporal evidence.

That&#039;s a long row to hoe.</description>
		<content:encoded><![CDATA[<p>Right.  They have no evidence that their hypothetical subgroup exist, they have no evidence that this subgroup correspond to their clients, they have no causal evidence linking  the &#8220;damage&#8221; to vaccines, except generally fuzzy temporal evidence.</p>
<p>That&#8217;s a long row to hoe.</p>
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		<title>By: Ms. Clark</title>
		<link>http://leftbrainrightbrain.co.uk/2008/05/autism-omnibus-and-shrinking-hypotheses/#comment-49993</link>
		<dc:creator>Ms. Clark</dc:creator>
		<pubDate>Wed, 14 May 2008 01:07:55 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=820#comment-49993</guid>
		<description>Yeah, Dr. Greenland is a reputable (as far as I can tell) epidemiology and statistics expert.  He spent a lot of time on the stand explaining exactly how a tiny, beensy, weensy subgroup of the &quot;1 in 150&quot; couldn&#039;t be measured in epidemiology, basically, these are my notes on what he said in during the cross examination by Ms. Ricciardella.  

&lt;blockquote&gt;&lt;b&gt;Greenland&lt;/b&gt;: If there is an effect it was concentrated in a small group to have gone undetected.
&lt;p&gt;&lt;b&gt;Ricciardella&lt;/b&gt;: But you have no evidence that such a group exists.&lt;p&gt;
&lt;b&gt;Greenland&lt;/b&gt;:  No.&lt;/blockquote&gt;

</description>
		<content:encoded><![CDATA[<p>Yeah, Dr. Greenland is a reputable (as far as I can tell) epidemiology and statistics expert.  He spent a lot of time on the stand explaining exactly how a tiny, beensy, weensy subgroup of the &#8220;1 in 150&#8221; couldn&#8217;t be measured in epidemiology, basically, these are my notes on what he said in during the cross examination by Ms. Ricciardella.</p>
<p>
<blockquote><b>Greenland</b>: If there is an effect it was concentrated in a small group to have gone undetected.</p>
<p><b>Ricciardella</b>: But you have no evidence that such a group exists.</p>
<p>
<b>Greenland</b>:  No.</p>
</blockquote>
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		<title>By: University Update - UCLA - Autism Omnibus and shrinking hypotheses</title>
		<link>http://leftbrainrightbrain.co.uk/2008/05/autism-omnibus-and-shrinking-hypotheses/#comment-49989</link>
		<dc:creator>University Update - UCLA - Autism Omnibus and shrinking hypotheses</dc:creator>
		<pubDate>Tue, 13 May 2008 20:57:18 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=820#comment-49989</guid>
		<description>[...] State University                           Autism Omnibus and shrinking hypotheses &#187;  This Summary is from an article posted at Autism Blog - Autism News, Science and Opinion on [...]</description>
		<content:encoded><![CDATA[<p>[...] State University                           Autism Omnibus and shrinking hypotheses &#187;  This Summary is from an article posted at Autism Blog &#8211; Autism News, Science and Opinion on [...]</p>
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		<title>By: Matt</title>
		<link>http://leftbrainrightbrain.co.uk/2008/05/autism-omnibus-and-shrinking-hypotheses/#comment-49987</link>
		<dc:creator>Matt</dc:creator>
		<pubDate>Tue, 13 May 2008 20:19:43 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=820#comment-49987</guid>
		<description>I&#039;m sorry--the comments above were Dr. Greenland, not Dr. Aposhian.</description>
		<content:encoded><![CDATA[<p>I&#8217;m sorry&#8212;the comments above were Dr. Greenland, not Dr. Aposhian.</p>
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