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	<title>Comments on: Generation Rescue&#8217;s Vaccinated/Unvaccinated Study</title>
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	<link>http://leftbrainrightbrain.co.uk/2010/06/generation-rescues-vaccinatedunvaccinated-study/</link>
	<description>Autism news and opinion</description>
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		<title>By: Science-Based Medicine &#187; Vaccines and infant mortality rates: A false relationship promoted by the anti-vaccine movement</title>
		<link>http://leftbrainrightbrain.co.uk/2010/06/generation-rescues-vaccinatedunvaccinated-study/#comment-166440</link>
		<dc:creator>Science-Based Medicine &#187; Vaccines and infant mortality rates: A false relationship promoted by the anti-vaccine movement</dc:creator>
		<pubDate>Mon, 09 May 2011 04:03:06 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=5632#comment-166440</guid>
		<description>[...] For example, last year Generation Rescue requested $809,721 from the Airborne settlement to set up a &#8220;vaxed versus unvaxed&#8221; study, despite the known difficulties with such a study and the low likelihood of finding anything [...]</description>
		<content:encoded><![CDATA[<p>[...] For example, last year Generation Rescue requested $809,721 from the Airborne settlement to set up a &#8220;vaxed versus unvaxed&#8221; study, despite the known difficulties with such a study and the low likelihood of finding anything [...]</p>
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		<title>By: Sullivan</title>
		<link>http://leftbrainrightbrain.co.uk/2010/06/generation-rescues-vaccinatedunvaccinated-study/#comment-88024</link>
		<dc:creator>Sullivan</dc:creator>
		<pubDate>Fri, 11 Jun 2010 00:25:47 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=5632#comment-88024</guid>
		<description>Dawn, 

nothing so exciting.  Just this post
http://leftbrainrightbrain.co.uk/2010/06/nih-funded-research-includes-search-for-possible-vaccine-autism-link/

which points out that a prospective study of environmental causation (and gene-environment interactions) is nearing completion.  That study, by Columbia University, includes vaccination as a factor to be tracked.

The question is--what does GR hope to do that isn&#039;t being done sooner and better by other groups?  Columbia is monitoring a cohort of 10,000 control families and 150-200 autistic kids.</description>
		<content:encoded><![CDATA[<p>Dawn,</p>
<p>nothing so exciting.  Just this post<br />
<a href="http://leftbrainrightbrain.co.uk/2010/06/nih-funded-research-includes-search-for-possible-vaccine-autism-link/" rel="nofollow">http://leftbrainrightbrain.co......tism-link/</a></p>
<p>which points out that a prospective study of environmental causation (and gene-environment interactions) is nearing completion.  That study, by Columbia University, includes vaccination as a factor to be tracked.</p>
<p>The question is&#8212;what does GR hope to do that isn&#8217;t being done sooner and better by other groups?  Columbia is monitoring a cohort of 10,000 control families and 150-200 autistic kids.</p>
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		<title>By: Dawn</title>
		<link>http://leftbrainrightbrain.co.uk/2010/06/generation-rescues-vaccinatedunvaccinated-study/#comment-88013</link>
		<dc:creator>Dawn</dc:creator>
		<pubDate>Thu, 10 Jun 2010 21:46:56 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=5632#comment-88013</guid>
		<description>@squillo:  wrong Dawn.  I don&#039;t twitter. You can send the check c/o Sullivan; he&#039;s one of the few who knows who I really am.  ;-)

@Sullivan:  stay tuned?  OOOOOHHHH!  Sounds interesting.  Does it have something to do with the emails you sent me a few weekds ago?</description>
		<content:encoded><![CDATA[<p>@squillo:  wrong Dawn.  I don&#8217;t twitter. You can send the check c/o Sullivan; he&#8217;s one of the few who knows who I really am.  ;-)</p>
<p>@Sullivan:  stay tuned?  <span class="caps">OOOOOHHHH</span>!  Sounds interesting.  Does it have something to do with the emails you sent me a few weekds ago?</p>
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		<title>By: Frank</title>
		<link>http://leftbrainrightbrain.co.uk/2010/06/generation-rescues-vaccinatedunvaccinated-study/#comment-87989</link>
		<dc:creator>Frank</dc:creator>
		<pubDate>Thu, 10 Jun 2010 15:47:22 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=5632#comment-87989</guid>
		<description>I&#039;m curious if/when Generation Rescue will be removing the now disproven theory that autism is preventable and is caused by immunizations and vaccines. I&#039;m sure by now we&#039;ve all seen the research that proves autism is genetic and occurs in the womb due to gene mutations and missing bits of DNA.
 
Please see this link for reference;
 
http://www.ctv.ca/CTVNews/TopStories/20100609/autism-genetic-changes-100609/
 
The sooner they correct their misinformation, the sooner we can prevent all the deaths that have been caused from preventable illnesses due to parents not having their children immunized because of their false claims.
 
Please stop Generation Rescue from contributing to so many senseless deaths.</description>
		<content:encoded><![CDATA[<p>I&#8217;m curious if/when Generation Rescue will be removing the now disproven theory that autism is preventable and is caused by immunizations and vaccines. I&#8217;m sure by now we&#8217;ve all seen the research that proves autism is genetic and occurs in the womb due to gene mutations and missing bits of <span class="caps">DNA</span>.</p>
<p>Please see this link for reference;</p>
<p><a href="http://www.ctv.ca/CTVNews/TopStories/20100609/autism-genetic-changes-100609/" rel="nofollow">http://www.ctv.ca/CTVNews/TopS.....es-100609/</a></p>
<p>The sooner they correct their misinformation, the sooner we can prevent all the deaths that have been caused from preventable illnesses due to parents not having their children immunized because of their false claims.</p>
<p>Please stop Generation Rescue from contributing to so many senseless deaths.</p>
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		<title>By: Sullivan</title>
		<link>http://leftbrainrightbrain.co.uk/2010/06/generation-rescues-vaccinatedunvaccinated-study/#comment-87904</link>
		<dc:creator>Sullivan</dc:creator>
		<pubDate>Wed, 09 Jun 2010 21:16:53 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=5632#comment-87904</guid>
		<description>Dawn--

stay tuned...</description>
		<content:encoded><![CDATA[<p>Dawn&#8212;<br />
stay tuned&#8230;</p>
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		<title>By: Squillo</title>
		<link>http://leftbrainrightbrain.co.uk/2010/06/generation-rescues-vaccinatedunvaccinated-study/#comment-87893</link>
		<dc:creator>Squillo</dc:creator>
		<pubDate>Wed, 09 Jun 2010 18:57:34 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=5632#comment-87893</guid>
		<description>@Dawn,

Where can I send the check?</description>
		<content:encoded><![CDATA[<p>@Dawn,</p>
<p>Where can I send the check?</p>
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		<title>By: Dawn</title>
		<link>http://leftbrainrightbrain.co.uk/2010/06/generation-rescues-vaccinatedunvaccinated-study/#comment-87892</link>
		<dc:creator>Dawn</dc:creator>
		<pubDate>Wed, 09 Jun 2010 18:45:32 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=5632#comment-87892</guid>
		<description>@Stephen: most respectable medical researchers &quot;poo-poo&quot; a &lt;b&gt; prospective&lt;/b&gt; vax/unvax study because doing one prospectively, with double-blinded researchers and participants, is very unethical. It is against the Treaty of Helsinki to withhold the &quot;usual and recommended&quot; medical care from a participant without their knowledge.

So, right away you would get a group that is either self-selected to have vaccines or not have vaccines.  And it would be almost impossible to randomize the groups, so they would not be equal.  This would mean a lot of potential confounders that would skew the results. 

So, you look at retrospective groups - those who didn&#039;t have vaccinations vs those who did. However, you still have to control for confounders.  And you need to randomize from groups that are different than those listed in the study.  Face it.  Most homeschooling families are going to be middle-to-upper income families. (Please - I didn&#039;t say ALL, don&#039;t start a flame war!) And yes,the Healthfirst families are well matched for that.  But you are ignoring the fact that, as was pointed out, families with autism/PDD-NOS may not be well represented in either group which again will skew the results.  

I know Prometheus had a good post about how he would do a study. 

Of course, if I had limitless funds and people (and could get this past an IRB - highly doubtful, actually -, here is how I would do it:
     Enroll EVERY child born in a 3 year period throughout the world.  
     At every doctor visit, if any, record what care the infant receives and why they are in for a visit (well care, vaccines, ear infection, etc).  The recorder will also document exactly what is any vaccines the child gets by listing all ingredients (barring the fetal monkey parts and other gross things...LOL!)
     The child is videotaped monthly at the office or at home for visual documentation of growth and development.
          Follow those children for 5 years (of course, in my ideal world, everyone participates and there are no drop outs...except for deaths.  Even in my ideal world, I am rational enough to realize children will die...from disease - vaccine preventable or not, from murder, from accidents, from war...)
     Tally those children and see who has more autism...IF either group has more.

(End dream world!)</description>
		<content:encoded><![CDATA[<p>@Stephen: most respectable medical researchers &#8220;poo-poo&#8221; a <b> prospective</b> vax/unvax study because doing one prospectively, with double-blinded researchers and participants, is very unethical. It is against the Treaty of Helsinki to withhold the &#8220;usual and recommended&#8221; medical care from a participant without their knowledge.</p>
<p>So, right away you would get a group that is either self-selected to have vaccines or not have vaccines.  And it would be almost impossible to randomize the groups, so they would not be equal.  This would mean a lot of potential confounders that would skew the results.</p>
<p>So, you look at retrospective groups &#8211; those who didn&#8217;t have vaccinations vs those who did. However, you still have to control for confounders.  And you need to randomize from groups that are different than those listed in the study.  Face it.  Most homeschooling families are going to be middle-to-upper income families. (Please &#8211; I didn&#8217;t say <span class="caps">ALL</span>, don&#8217;t start a flame war!) And yes,the Healthfirst families are well matched for that.  But you are ignoring the fact that, as was pointed out, families with autism/PDD-NOS may not be well represented in either group which again will skew the results.</p>
<p>I know Prometheus had a good post about how he would do a study.</p>
<p>Of course, if I had limitless funds and people (and could get this past an <span class="caps">IRB </span>- highly doubtful, actually -, here is how I would do it:<br />
Enroll <span class="caps">EVERY</span> child born in a 3 year period throughout the world.<br />
At every doctor visit, if any, record what care the infant receives and why they are in for a visit (well care, vaccines, ear infection, etc).  The recorder will also document exactly what is any vaccines the child gets by listing all ingredients (barring the fetal monkey parts and other gross things&#8230;LOL!)<br />
The child is videotaped monthly at the office or at home for visual documentation of growth and development.<br />
Follow those children for 5 years (of course, in my ideal world, everyone participates and there are no drop outs&#8230;except for deaths.  Even in my ideal world, I am rational enough to realize children will die&#8230;from disease &#8211; vaccine preventable or not, from murder, from accidents, from war&#8230;)<br />
Tally those children and see who has more autism&#8230;IF either group has more.</p>
<p>(End dream world!)</p>
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		<title>By: Squillo</title>
		<link>http://leftbrainrightbrain.co.uk/2010/06/generation-rescues-vaccinatedunvaccinated-study/#comment-87889</link>
		<dc:creator>Squillo</dc:creator>
		<pubDate>Wed, 09 Jun 2010 18:23:08 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=5632#comment-87889</guid>
		<description>Forgive my ignorance, but why wouldn&#039;t GR set up a foundation to fund such research rather than attempting to direct it themselves? They clearly don&#039;t have the in-house expertise, and anyone they bring on board directly is likely to be tainted--fairly or unfairly--as biased.

Wouldn&#039;t a grant be more likely to attract real experts to design and conduct the study? Via a grant process, GR could ensure the study design was to their liking and relatively free of the COIs they object to in other research.</description>
		<content:encoded><![CDATA[<p>Forgive my ignorance, but why wouldn&#8217;t GR set up a foundation to fund such research rather than attempting to direct it themselves? They clearly don&#8217;t have the in-house expertise, and anyone they bring on board directly is likely to be tainted&#8212;fairly or unfairly&#8212;as biased.</p>
<p>Wouldn&#8217;t a grant be more likely to attract real experts to design and conduct the study? Via a grant process, GR could ensure the study design was to their liking and relatively free of the COIs they object to in other research.</p>
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		<title>By: Kev</title>
		<link>http://leftbrainrightbrain.co.uk/2010/06/generation-rescues-vaccinatedunvaccinated-study/#comment-87850</link>
		<dc:creator>Kev</dc:creator>
		<pubDate>Wed, 09 Jun 2010 07:22:02 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=5632#comment-87850</guid>
		<description>Stephen, its not a case of hiding anything. As Sullivan says in his blog entry, a study like this is very very difficult to do and do well. Many of us fear a badly designed study that will just tell those bankrolling it what they want to hear.</description>
		<content:encoded><![CDATA[<p>Stephen, its not a case of hiding anything. As Sullivan says in his blog entry, a study like this is very very difficult to do and do well. Many of us fear a badly designed study that will just tell those bankrolling it what they want to hear.</p>
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		<title>By: David N. Brown</title>
		<link>http://leftbrainrightbrain.co.uk/2010/06/generation-rescues-vaccinatedunvaccinated-study/#comment-87848</link>
		<dc:creator>David N. Brown</dc:creator>
		<pubDate>Wed, 09 Jun 2010 05:22:16 +0000</pubDate>
		<guid isPermaLink="false">http://leftbrainrightbrain.co.uk/?p=5632#comment-87848</guid>
		<description>&quot;If there was nothing to hide there would not be such a stink about it.&quot;
The ones making a stink are &quot;vaccine blamers&quot; whose claims have already been rejected by science.  They are also the ones who, on conducting an actual survey, committed outright fraud. (See &quot;Stupid Like a Fox&quot; at Evil Possum.) They, in short, are the ones with things to hide.</description>
		<content:encoded><![CDATA[<p>&#8220;If there was nothing to hide there would not be such a stink about it.&#8221;<br />
The ones making a stink are &#8220;vaccine blamers&#8221; whose claims have already been rejected by science.  They are also the ones who, on conducting an actual survey, committed outright fraud. (See &#8220;Stupid Like a Fox&#8221; at Evil Possum.) They, in short, are the ones with things to hide.</p>
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