Archive | April, 2006

Autism ‘Epidemic’ Groups Turn To Misrepresentation

5 Apr

Following publication of the Shattuck paper casting doubt on the evidence for an autism epidemic:

The mean administrative prevalence of autism in US special education among children ages 6 to 11 in 1994 was only 0.6 per 1000, less than one-fifth of the lowest CDC estimate from Atlanta (based on surveillance data from 1996). Therefore, special education counts of children with autism in the early 1990s were dramatic underestimates of population prevalence and really had nowhere to go but up. This finding highlights the inappropriateness of using special education trends to make declarations about an epidemic of autism, as has been common in recent media and advocacy reports.

Source.

The usual suspects have begun to trot out the usual ploys to try and misrepresent and obscure. The National Autism Association write:

A study published today in Pediatrics, “The Contribution of Diagnostic Substitution to the Growing Administrative Prevalence of Autism in US Special Education,” suggests that autism diagnoses haven’t actually risen over the past two decades, despite *growing and credible scientific evidence to the contrary*. In addition to the study’s *weak methods and erroneous conclusions*, questions have now arisen over possible *failure to disclose conflicts of interest* and *recent findings that data from previous autism projects with which current study author Paul Shattuck has been associated were fabricated*.

So first lets tackle the ‘growing and credible scientific evidence to the contrary’. Where is it? Where does it exist? Note that NAA totally fail to name, or even _reference_ this ‘growing evidence’.

They also mention ‘weak methods and erroneous conclusions’ yet again failing to illustrate what these ‘weak methods’ are or why they are weak. As far as erroneous conclusions go, that seems to be NAA double-speak for ‘things we disagree with but can’t back up’.

But what about ‘failure to disclose conflicts of interest’? NAA say:

Although the article states that Dr. Shattuck has indicated he has no financial relationships relevant to the article, NAA has learned that he was a Merck Scholar Pre-doctoral Trainee from 1999-2003, and in 2003-2004 he successfully applied for $530,000 from the Centers for Disease Control and Prevention (CDC)

Somebody remind me again – what year is this? 2003? 1999? Or is it 2006? two years after Dr Shattuck had *an alleged* financial relationship with Merck.

UPDATE: Orac Provides the following: _”Oooh, Shattuck received money from the evil Merck to support his training! Except that the Merck we’re talking about seems to be not the evil drug company but rather a nonprofit organization, the John Merck Fund, which supports research into a variety of areas, particularly developmental disabilities.”_

By comparison, Wendy Fournier, president of the NAA has an ongoing, established financial relationship with David Kirby – author of Evidence of Harm – as does Safe Minds. Claire Bothwell, Chair of the NAA, works(worked?) for Waters and Kraus, lawyers who solicit thimerosal plaintiffs over the internet.

Lastly, what about ‘recent findings that data from previous autism projects with which current study author Paul Shattuck has been associated were fabricated’? Sounds damning, until you read on:

Although he was not personally implicated, Dr. Shattuck’s former research partner, a graduate student at the University of Wisconsin’s Waisman Center, was recently disciplined by the Health and Human Services Office of Research Integrity for scientific misconduct due to fabrication of data. Dr. Shattuck and others published several articles and delivered scientific presentations using data from the project in question

So someone that Shattuck once quoted got themselves in trouble. Thats hardly what I’d call

…with which current study author Paul Shattuck has been associated…

There’s also no indication that these studies Shattuck referenced, or the presentations he made which referenced them had _anything at all_ to do with autism.

The press release goes on to say:

Given the rocky history of the CDC and the autism community, failing to mention the author’s ties to this agency is a glaring omission that requires an explanation,” commented NAA board chair Claire Bothwell. “Clearly, the CDC has a vested interest in deflecting attention from the possibility that children injured by mercury-containing vaccines ended up with autism diagnoses which fueled autism rates off the charts

First of a message to the NAA, Safe Minds, Generation rescue etc – *you are not the autism community* . You represent a small subset of parents. Thats it. What you have is a good PR campaign and a few pet journalists.

Secondly, its clearly the case that several anti-vaccine groups such as NAA, SafeMinds etc are beginning to get very very jumpy and have a vested interest in deflecting attention away from the increasing evidence that there has been _no epidemic of autism_ and that autism is not caused by thiomersal in vaccines. Autism rates are not ‘off the charts’ – the charts were simply never big enough to start with.

These groups need to stop politicising the issues, need to stop painting themselves as ‘the autism community’ and need to stop this pointless and utterly transparent attack on any credible science that undermines their isolationist position.

Open Letter To Andrew Wakefield

4 Apr

Dear Mr Wakefield,

Following your announcement of a link between the MMR vaccine and autism, uptake rates of this vaccine in the UK have fallen to amongst the lowest in Europe:

Take-up rates of the jab dropped throughout the UK, down to less than 70% in some areas, after a small-scale study published in The Lancet in 1998 by Dr Andrew Wakefield suggested a link to autism.

Source.

In 2004, mumps cases in the England and Wales rose from 4,204 in 2003 to 16,436 in 2004, nearly a four-fold increase.

And in the first month of 2005, there were nearly 5,000 cases. Most were among young adults born before 1988 and who would, therefore, not have been offered MMR as a child. In the second paper, Dr Ravindra Gupta, from London’s Guy’s and St Thomas’, working with colleagues from King’s College London, found cases have also occurring in very young children who would have been eligible for the MMR – measles, mumps and rubella – vaccine…..Dr Gupta (…) said uptake of MMR among two-year-olds in the UK fell from around 92% in early 1995 to around 80% in 2003/4.

Source.

In October 2004, experts predicted that due to falling vaccination uptake, the UK would start to suffer from ‘small outbreaks’:

The medical newspaper Pulse has warned that there could be a measles epidemic this winter on a scale last seen in the 1960s. It said that lowering levels of immunity meant as many as 12% of children and 20% of adults could be hospitalised if infected by measles.

Source.

And now, this year, 18 months after this warning, we have the UK’s first measles induced fatality in 14 years.

The 13-year-old who died last month lived in a travellers’ community. It is thought that he had a weakened immune system; he was being treated for a lung condition. The boy died of an infection of the central nervous system caused by a reaction to the measles virus. The Health Protection Agency described his death as shocking.

Source

The Times also says that of the 72 reported measles cases last month, 9 required hospitalisation – this tallies almost exactly with the 2004 prediction of a hospitalisation rate of 12%.

I have a few questions for you Mr Wakefield.

Do you accept that there is a strong causative correlation between the falling MMR vaccine uptake and the rise in both mumps and measles? If you do not, could you please explain why not. If you do could you please explain what you feel is your role in these matters.

Is it true that, as reported by Brian Deer in the Times and in the Channel 4 current affairs programme ‘Dispatches’, that you received up to £55,000 to find scientific evidence of a link between MMR and autism and that you did not disclose you were being funded through solicitors seeking evidence to use against vaccine manufacturers?

Is it true that the vast majority of your subjects from the Lancet study were not, as you claimed, captured through the normal referral process, but actually supplied to you by lawyers representing these people and their families in vaccine litigation?

Is it true that up to nine months prior to the publication of your paper showing a link between the MMR vaccine and autism that you and the Royal Free (where you conducted your research) filed numerous patent applications which were alternatives to the MMR vaccine? If you did, would you consider it a lucky guess that led you to do this seeing as your MMR paper had yet to be published?

Do you believe, like your collaborator Hugh Fudenberg, that:

Some parents would rather see their kid die than live as a severely autistic.

Source.

These are serious matters Mr Wakefield. I’m aware that you are pursuing three court cases related to these matters (although at least one is currently stayed) and you are also due to be investigated by the GMC sometime this year but as the parent of an autistic child – in short exactly the sort of person you claim to want to help – I need answers now. What I read of you indicates wrong doing on a grand scale. If these things are established to be true you are guilty of not only extreme medical negligence but also of betraying thousands of parents and forcing thousands of autistic children to undergo totally unnecessary and highly invasive medical procedures.

You need to account for yourself Mr Wakefield. Please don’t wait for more children to be hospitalised or die.

Meme Clobbered – Where Was I?

3 Apr

H has meme clobbered me and as I took the piss out of 37 Signals so mercilessly I can no loger cry off such things. Damn you karma!!

Where Was I One Year Ago?

One year ago I worked for a financial services company as their in house designer/developer. We were also getting our daughter established in a mainstream school, my wife was six months pregnant and I had gone through about 3 re-designs of this site in a month.

Where Was I Five Years Ago?

2001 right? Erm….I was working for a design agency (clients included Disney, Nat West, Jarvis and others) churning out very dodgy Flash based websites and living the dotcom dream. Shorlty afterwards I was laid off. The dotcom nightmare.

Where Was I Ten Years Ago?

Christ. In 1996 I was at University doing my degree and was doing a bit of web stuff to make ends meet. I had just met Naomi. I was thinner. I was fitter. I had a better blood pressure. Other than that I cannot remember/am not saying.

Its customary at this time for me to clobber three other people with this meme. I shall therefore choose one design blogger, one autism blogger and one skeptic blogger.

Dan Olmsted And The Autisms

2 Apr

No, not a new rock group.

Dan Olmsted is a UPI reporter who forms part of the Holy Trifecta of Media – the other two prongs being Evelyn Pringle and of course, good old honest, impartial David Kirby.

Dan Olmsted burst onto the scene with the attention getting ‘Amish Anomaly’ wherein he discovered through an exhaustive and meticulous system of asking a water purifier salesman if he knew of any, that only vaccinated Amish people are autistic.

The ‘Amish Anomaly’ caught peoples imagination – ‘if vaccines don’t cause autism then why don’t the Amish have more autistic people’? was the cry on everyones lips – conveniently brushing aside the fact that Olmsted’s system was about as much use as a chocolate fireguard – and also conveniently brushing aside the fact that the Amish have a virtually closed gene pool. But of course all right thinking people know that autism was invented by Eli Lilly in 1931 thus these facts don’t make any difference.

So it must’ve been strange for these ‘right thinking people’ when a bunch of autistic people turned up right in the same area Dan Olmsted performed his meticulous research. Only these people were found as part of a research paper summarised here.

A study of Old Order Amish children has identified the genetic mutation that causes a previously unknown disorder, with seizures that progress to autism and retardation.

How could this be? Surely a reporter as experienced as Dan Olmsted with autism couldn’t have missed this? Here’s Dan’s primary source – the water purifier salesman – again:

I’ve got to tell you, I have never seen an autistic Amish child — not one,” he said. “I would know it. I have a strong medical background. I know what autistic people are like. I have friends who have autistic children.”

And here’s the science again:

A study of Old Order Amish children has identified the genetic mutation that causes a previously unknown disorder, with seizures that progress to autism and retardation.

Huh. Something of an anomaly. Or maybe – just maybe – Dan Olmsted’s source was full of shit.

So how _could_ Dan’s source have screwed up? Maybe because he _doesn’t_ know autism as well as he thinks he does. These children were ‘secondary’ autistics: those who’s autism is a comorbidity in itself (example: in this page autism is a comorbidity of Down’s Syndrome). In the case of the children in this study, their autism was secondary to their seizures.

However, that does _not_ equate to them not being autistic any more than an autistic person with a comorbidity of asthma is not asthmatic.

This is _exactly_ why reporters words shouldn’t be enshrined as gospel truth. If Dan Olmsted had noted he’d not found a lot of autistic people amongst the Amish and left it at that or even followed it up a bit more responsibly then there would be no problem. However, as befits a good friend of SafeMinds Director Mark Blaxill, he went in with a preconceived agenda and thus found (or failed to) exactly what he wanted.

Read more at Prometheus’ place, Autism Diva’s place and Dad of Cameron’s place.