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Lenny Schafer’s Cognitive Dissonance

27 Mar

Another day, another Schafer Mercury Report.

Lenny has a dig at the recently published Afzal et al paper ‘Absence of detectable measles virus genome sequence in blood of autistic children who have had their MMR vaccination during the routine childhood immunization schedule of UK’:

It is hard to understand why the authors claim that their study of MMR virus in the blood “failed to substantiate” the reports by Andrew Wakefield, and by now any other researchers — that they found the MMR virus in gut biopsy samples from autistic children.It is obviously far easier to collect blood samples than to collect biopsy samples from the GI tract, which is an invasive procedure with risks. If blood were a suitable source to look for the MMR virus, Wakefield would have used blood in his study

I have no doubt it _is_ hard for Mr Scahfer to understand. It was hard for me to understand too. So I asked someone.

…measles is a lymphotropic virus, even more so for the vaccine strain which has been selected to exploit the CD46 cellular receptor. If there is a persistent MV infection the most logical place to detect it is in cells that it is most adept at infecting. Lymphocytes

Lymphocytes are a type of blood cell. Of course, given that, Lenny’s question re: Wakefield becomes unintentionally hilarious:

If blood were a suitable source to look for the MMR virus, Wakefield would have used blood in his study

Only if it occurred to him Lenny, only if it occurred to him.

Simple translation: Yes, this new study does not replicate Wakefield examining the gut. This is because there’s no need to. Blood cells are more likely to show infection than the gut. If Wakefield or Bradstreet wanted to make a special case for the gut then they failed to do so.

Interestingly, Afzal et al approached both Wakefield and Bradstreet to collect samples of the tissue they collected but they never responded to the request:

The groups of investigators that either had access to original autism specimens or investigated them later for measles virus detection were invited to take part in the study but failed to respond. Similarly, it was not possible to obtain clinical specimens of autism cases from these investigators for independent investigations.

Cynic that I am, I have to wonder why. Too busy to ask a research assistant to locate, package up and send off some samples? Or maybe too worried about what a decent scientist would reveal.

Amusingly, Lenny next attacks Parental Perspectives on the Causes of an Autism Spectrum Disorder in their
Children
which recently reported that a low percentage of parents blamed their childs autism on vaccines:

This immense undertaking involved collecting questionnaires from a grand total of 41 parents! It is remarkable that as many as 16 of the respondents said vaccines are a cause of autism. How many questionnaires were given to parents who simply discarded them, knowing that a survey conducted by a University Department of Medical Genetics has little interest in learning what parents think about the role of vaccines in causing autism?

Can anyone remind me again how many kids were involved in the original Wakefield paper? Was it 41? No? 20? No?

Twelve?

Twelve.

Lets also not forget that another recent study looked at what treatment options parents were pursuing. Only 7% were pursuing detoxification (chelation etc). That was from a total of 552 returns.

Lenny seems disturbed that he is part of a minority. I’d advise him to get used to that feeling. As decent science like Afzal et al continues to refute the poor science that precedes it, people like Lenny will become more and more isolated.

DAN! Protocol For Dummies

20 Mar

Whenever anyone else hears the word ‘DAN!’ with that little exclamation mark do they go ‘DAN! – DAN! – DAN – DAN!’ to the opening four bars of the theme to ‘Dragnet’? No? Ah well, just me then.

Ken Aitken is a psychologist. He’s also a DAN! Doctor. One doesn’t need to be an actual Doctor to be a DAN! Doctor apparently:

As for choosing a DAN!, it just depends on what type of treatment you are looking for. DAN!’s that are MDs or DOs are typically going to be much more into testing and genetics and lots of expensive and invasive stuff. This, of course, is a gross generalization and isn’t necessarily true of all DAN! MDs, but rather something to be cautious of. A DAN! who is a homeopath or naturopath is typically going to do things more naturally and less invasive. Again, it’s a generalization. There are chiropractors, allergists and other types of doctors that are DAN!s as well, so it is really the type of doctor and treatment that best suits your needs. Many people go with a MD or DO because they can get insurance coverage for some of the services.

Homeopaths and Naturopaths doing things ‘naturally’. Heh. Does this lack of training in medical matters prevent them from performing things like chelation (source as above)?

…which is why we went with a homeopath/naturopath…….We decided to get the mercury out because I knew that Seth had had way too much put into him and it wasn’t coming out at all (he’s a non-excretor).

Homeopaths and Naturopaths doing chelation. Cool.

I talked to one yesterday (a DAN doctor mind you) and how he got qualifications to be one is beyond me. He told me has a couple of autistic patients and knows of the chelation process. If this is all that is required to be a DAN doctor then I don’t see a distinct advantage to them either.

Source.

Is your mind boggling yet? Here’s the reply to this commenter (source as above):

I think that being on the DAN list (in the past) meant something like that the person had attended some DAN training– or something rather general like this. Someone (in some post, somewhere) who went to the recent DAN conference wrote about that there is/was some discussion afoot to try to improve on this and make the
info on doctors more useful (or more detailed….or something??)

This doesn’t sound like a recipie for disaster at all. Was Roy Kerry a DAN! Doctor? I don’t know.

I came across some priceless websites pushing the DAN! protocol. They had numerous things in common, chiefly the disclaimer – all variations on the theme of:

this is not medical advice

Which is odd because from that point on, they mostly plough into what can only be thought of as _advice_ about what _medication_ an autistic child should take. There’s a fairly representative sample of what a dutiful DAN! Doc should do on the website of Miriam Jang MD. First, the usual copout from responsibility:

At this point, I would like to point out that this is not medical advice, even though I am a Medical Doctor. Rather, this is a wish for your child or your loved one(s) to have the advantage of what took us eight years to discover. Please take this as a medical disclaimer. All suggestions here should be done at your own risk.

‘Own risk’. Right. Or actually – wrong. She means the risk of the child receiving the treatment. Thats whos health will suffer when if it all goes wrong.

Dr Jang decides to lead off with some impressive science:

In both Chinese medicine and Ayurvedic medicine, the sages believed that there were only two ways to health: one was to correct deficiencies; the other was to get rid of toxicities.

Ayurvedic? What the hell?

This ancient art of healing has been practiced continuously for over 5,000 years. The principles of many natural healing systems now familiar in the West, such as Homeopathy and Polarity Therapy, have their roots in Ayurveda. Ayurvedic practices restore the balance and harmony of the individual, resulting in self-healing, good health and longevity.

So, DAN! Doctors are homeopaths and naturopaths who practice er, Polarity Therapy. Polarity Therapy? What the hell?

Polarity Therapy is a comprehensive health system involving energy-based bodywork, diet, exercise and self-awareness. It works with the Human Energy Field, electromagnetic patterns expressed in mental, emotional and physical experience.

Riiiight. OK. Back to er, Doctor (?) Jang. Basically, there’s a load of stuff with no cites – such as:

An important finding is that about 85 percent of Autistic kids are high in Copper and low in Zinc. Furthermore, these kids are very low in an important protein call Metallothionein, or MT Protein.

Hmm. Searching PubMed for ‘Metallothionein autism’ reveals two results. One is an inaccessible review and one is a free PDF published in the confidence inspiringly named ‘Alternative Medecine Review’. A Google search for the same reveals the predicted circus of quackery.

Except….another one of the mercury/autism darlings, Vijendra K. Singh has a paper that states:

serum level of MT did not significantly differ between normal and autistic children. Furthermore, autistic children harboured normal levels of anti-MT, including antibodies to isoform MT-I (anti-MT-I) and MT-II (anti-MT-II), without any significant difference between normal and autistic children.

A dilema, no? (You can read more on this paper here.)

Dr Jang continues with:

I will include a list of supplements that Marky is taking. There are many protocols, with many rationales. When we write down the dosages, please take into consideration that Marky is 11 years old and weighs 75 pounds. Please adjust your dosages according to your child’s weight.

Marky is her son. But isn’t it amazing how a DAN! Doctor is assuming parents know *how* to adjust medications for weight – and is happy to trust them to do so without medical supervision or even consultation!

Towards the end of her piece she says:

Please remember that, if you introduce your child to a new supplement, it is not unusual for the child to experience some adverse effects for a short while…When this happens, it does not necessarily mean that you should discontinue the supplement, unless the adverse effects are dangerous, or persistent….If there are adverse effects, stay at this dose until the adverse effects are gone, then proceed to a slightly higher dose, etc.

So there may be adverse effects but don’t stop unless the adverse effects are dangerous, instead stay on the same dose until the adverse effects are gone. I can’t imagine any Doctor thinking this is good advice. Interestingly, the following appeared from Dr Jang as part of an email newsletter:

I would like to start with some very serious news: we do have to be careful of Vitamin A toxicity with our sweet kids. There is a child with reported Vitamin A toxicity that was so severe that the child had to be hospitalized for 12 days.

Her patient? I wonder. Maybe the practitioner (whomever s/he was) read her advice to ‘stay on the same dose until the adverse effects are gone’.

Dr Jang tells us in relation to supplements that:

We noticed a difference in Marky in less than a week.

And yet later on she says:

In addition, you may not see the beneficial effects of these supplements for a period of time.

Something of a glaring contradiction. Which is true?

Anyway, having expounded all this good advice, Dr Jang closes with:

So, be curious and be persistent. Take good care of yourselves so that you can endure this arduous journey called “Autism”!

Yes, be curious – try everything that takes your fancy. Be persistent – whats a little Vitamin A poisoning between friends? And above all take good care of _yourselves_ so that _you_ can endure this journey…..except, its not _you_ who’s undergoing all these treatments is it? Its your child.

Dr Jang is also a big clay bath fancier (clay baths cure autism? Who knew?)

“…I have put a huge number of patients on these clay baths and the levels of heavy metals – mercury, lead, arsenic, aluminum, and cadmium have come down dramatically…I have been monitoring the levels of metals using all three methods (TD DMPS, oral DMSA and clay baths)and the clay baths are way faster in the removal of metals”.

Hoooo boy! Rashid’s going to be plenty pissed with her. Better than TD DMPS? Surely not! Why not use both? Smother your child with TD DMPS and then wash that stuff off in a nice clay bath? At least your child will have a nice happy splash in a bath.

So, Ken Aitken – welcome to your new role as a Dan! Doctor. I feel sure you can uphold the strong scientific standards your colleagues demonstrate.

Paul Shattock: What The…?

14 Mar

I recently had occasion to quote some of Mr Shattocks work. Namely, the case studies he diagnosed autism from in Victorian Britain. These were the papers that John Best Jr felt were lies. What I didn’t tell John until after he had a good rant and (if I recall) called the author ‘some nut’ was that Mr Shattock is a staunch believer in the MMR/Thiomersal/autism connection.

Some nut indeed.

Paul Shattock has extensive ties to Andrew Wakefield. Both feel that the MMR has some role to play in autism and Mr Shattock is a promoter of what he terms:

…some of the unorthodox forms of biomedical intervention currently being applied to autism.

Sunderland.

Dr Micheal Fitzpatrick comments:

Metabolic theories continued to attract a following in the shadowy area of alternative and fringe therapies, particularly in the USA. The cult of ‘orthomolecular psychiatry’ emerged out of these theories and popularised the treatment of a range of psychiatric problems with a high dose of vitamins, amino acids, minerals and other diets and dietary supplements. It is out of this tradition, which has little concern for the rigours of scientific research, that Mr Shattock’s studies have emerged.

Like the Geier’s, Paul Shattock publishes his research in some strange places (source as above):

It is impossible to evaluate Mr Shattock’s findings because they have not been published in any form. Indeed, virtually all his work has been published in the ‘grey literature’, in journals which have no formal process of evaluation or peer review.

It seems the paper he published and I quoted to John is a rare exception in a sea of vanity publishing. Indeed, Paul Shattocks Sunderland team website carries links to places like nomercury.org – hardly an informed or non-partisan choice.

Paul Shattock himself is an interesting figure. Father of an autistic child himself, he refuses to publish his work until he has studied 1,000 children. However that didn’t stop details of his work and preliminary findings mysteriously appearing (source as above):

Mr Shattock’s research entered the public realm, via journalists sympathetic to the anti-MMR campaign

But perhaps the greatest mystery about Paul Shattock is what the letters after his name mean. Sunday Times and Channel 4 Dispatches journalist Brian Deer asks the same question:

(I)….ran a Google search for DipAgVet, the latest qualification sported by Mr Paul Shattock, who specialises in urine tests.

For details of what came back and how you can help Mr Deer, go visit his site and take a guess.

Isabella Thomas Gets Her Day In Court

10 Mar

Isabella Thomas of the anti-vaccination group JABS has got her day in court.

She claims that the MMR jab,

led to her sons developing autism

in the careful phrasing of the BBC.

The proceedings will begin in June. It should be a very interesting case for all of us involved from whatever perspective we look at the MMR angle from. She also told the BBC that:

…she noticed he was experiencing difficulty shortly after he had the vaccine…..The infant’s condition gradually deteriorated from that moment onwards and he was eventually diagnosed with autism,” she said

A bit short on facts as an article, I decided to see if I could find out a bit more regarding this ‘gradual deterioration’ in terms of what form it took.

In November 2003, the then (and current) Lib Dem MP for Lewes (Ms. Thomas’ constituency) Norman Baker, presented a speech concerning Ms Thomas to the Health Minister (then Dr Reid if memory serves) in which he outlined her various issues with how her sons had been treated by the medical establishment. Her MP sums up:

My constituent believes, rightly or wrongly, that the reactions that have been caused in her children and which have led to these, it seems, permanent conditions are a result of MMR. She holds that view very strongly and communicates it to those in the health service. She feels that because she holds that view, her children are effectively being denied effective treatment to deal with their conditions until such time as she is prepared to deny that MMR is the cause. That may be a misconception on her part, but that is what she believes.

Mr Baker is obviously being as tactful to Ms Thomas’s belief system as he possibly can be which is commendable behaviour in an MP but I agree with his inference that its only because she holds the view that MMR ‘led to’ her sons autism that she feels she’s having treatment withheld for _that_ condition (not autism, but MMR induced autism).

More interestingly, he also details her sons ‘gradual deterioration’. This is a description of Michael, her eldest.:

…he was like a wild animal; he screamed when anyone touched him and cried day and night. He has been diagnosed with regressive autism and has an obsessive-compulsive disorder. He suffers from auditory hallucinations, increased clumsiness, chronic bowel disease, temperature control problems, severe headaches, loss of memory, breathing problems and rashes.

And Terry, Michael’s younger brother:

During the night after the vaccination, Terry suffered a fit and within a week he developed excessive temperature swings and loss of skills. Before the vaccination, he was potty trained, but he regressed the very next day. Within two weeks he began to suffer from constipation and chronic diarrhoea. Within a month he appeared clumsy and walked into doors. He stopped talking and would become completely silent. He no longer indulged in pretend play. He now suffers from fits, jaundice when ill, chronic bowel disease, very high fevers, rashes, regressive autism and excessive thirst.

Both boys are said to have:

the measles virus, consistent with the vaccine strain

found in their bowels and blood in Michaels case.

As far as I read it, *none* of Michaels symptoms match those of any known diagnostic criteria of autism. Two, maybe three out of the eight listed above match comorbidities sometimes associated with autism.

Terry’s symptom list is more intriguing and contains the hotly debated ‘regressive autism’. It also lists it _as_ a symptom, indicating that the other symptoms haven’t _caused_ it but exist alongside it. If we take the other as possible indicators of autism then only one ‘he no longer indulged in pretend play’ speaks openly of autism to me. Again, two, possibly three of his listed symptoms out of the thirteen or so listed speak of sometime comorbidities.

Its an established fact that vaccines can cause injury. Could they have caused these injuries? Of course they _could_ . But did they? I don’t know. I would imagine that Ms Thomas filled out a form for the Vaccine Damage Payment Unit and I would imagine that, as in all cases, they performed an investigation and found her claim unsubstantiated. I could be wrong though, maybe she didn’t but seeing as JABS link to the VDPU and encourage people to make such a claim it would seem logical to assume she has. if they rejected her claim that means they don’t agree that the MMR jab caused either of kids problems.

But lets say they did, just to play devils advocate. As the listed symptoms seem utterly dissimilar to those used to diagnose autism I’m unsure how Ms Thomas hopes to establish a causative link at all. Should be an interesting case to watch all the same.

McScience

3 Mar

Yesterday, my fellow countryman Mike Stanton left the following comment in response to a previous commenter about his belief regarding how his child had become autistic:

There may not be a single answer. But that does not mean we can pick any answer we like. There has to be some scientific validity to any hypothesis.

This is such a good comment. It reflects something I’ve felt increasingly over the last year or so – the increase in pseudo-scientific theories posed as a ‘menu’ for parents to choose from. It reminds me of sauntering up to the counter at McDonalds and saying – “I’ll have one of those, one of those and one of those.”

I recently came across a post made on the Onibasu list which illustrates my point. This is the signature of the poster in question. Its a list of treatments she’s trying on her child:

My son is using M-B12 (Hopewell) since Dec 2003, Wellness Essential GSH (had been using TD-Glut but levels were always low), TD-DMSA (3 on and 4 off – 8 hr schedule) (Lee Silsby) since Oct 2005, (Used TD-DMPS Jan 2005 ?Oct 2005) TD-ALA (Lee Silsby) since Oct 2005, TD-LDN (Wellness) Since Oct 2005, (High Tech Health) FIR sauna, Magnetico bed, High Tech Health’s water machine, and a lot of supplements.) GFGFSF diet.

The post in question is also asking about Lupron. Thats a total of 12 separate treatments, ‘a lot of’ supplements and she probably is in the process of adding Lupron to that list as we speak.

And can you Supersize me please?

What worries me is even a bog-standard bottle of Asprin has a warning on it about responsible use. Is it really sensible to risk giving one’s child such a massive cocktail of drugs on the word of someone who quite obviously is more interested in money than science?

Medicine shouldn’t be such a pick and mix affair. Its quite worrying about what this reveals about how the West’s perception of doctors has changed. Doctors who have undergone 7 years plus of training are viewed with suspicion and sued at the drop of an opinion whilst ‘doctors’ who have shops rather than practices are lauded as heroes.

How did it come to this? When did McScience start to replace science? How did it come to pass that the process of peer review (designed to give a good _starting point_ to a paper) meant nothing and the process of buying an entry in a pseudoscience rag or buying a misleading advertmeant everything?

I’m nobodies scientist. It takes me longer to understand the science because I need to go through it time after time so I understand all the words and understand the implications. I ask questions of actual scientists and get them to translate for me so it stands to reason to me that for an article to be peer reviewed in a decent journal assures that the standard of science in that article will be fairly high. It might not make the paper _right_ , but at least we can be sure its been thought through properly.

Surely that needs to be the absolute baseline of quality we should come to expect for papers that discuss such important questions. Otherwise we really do end up at the counter of McScience – like kids in a sweet shop, taking what we think we’ll like rather than what we need.

Peter Fletcher, Melanie Phillips and the Daily Mail – A Cracked Facade

9 Feb

The Daily Mail published another MMR piece earlier this week. As usual it had the predicted results in that it stirred up the usual frenzy of illogic and fallacy.

Why do I say that?

In order to explain we need to fast-forward a couple of days to where Melanie Phillips, Andrew Wakefield’s staunchest media supporter in the UK, published her own follow up to the Mail story. I urge you to go read both pieces now before you read the rest of this.

OK, done? Good.

So lets talk about what was said. Basically, the gist of both articles is now the medical community in the UK _have_ to take the MMR link seriously because Dr Peter Fletcher, ex-Chief Scientific Officer at the Department of Health has said a few things about it.

On the face of it thats pretty impressive – this isn’t some no-nothing from nowhere – this is an *ex CSO*. But once you get past the fact of who he _is_ and start to isolate what he’s actually _saying_ then, to borrow a phrase, the facade starts to crack.

First is the fact that this sort of argument – based on his good standing in the past – is a sort of reverse Argumentum Ad Hominem in that it is argued that it is equally or of more importance regarding who Dr Gordon _is_ as oppose to what he _says_. This is, of course, a fallacious position from which to start.

So what does he (and the original article) actually say?

[Dr Gordon]….has accused the Government of “utterly inexplicable complacency” over the MMR triple vaccine for children.

Thats simply an assumption based on his circular reasoning that the MMR has routine or above average negative effects: as an argument it relies on the reader agreeing that there is a case for the Gvmnt being complacent in the first place. Since the establishment of this case _is whats actually being debated_ its safe to ignore this as pre-conceived bias.

[Dr Fletcher]…..said if it is proven that the jab causes autism, _”the refusal by governments to evaluate the risks properly will make this one of the greatest scandals in medical history”_.

Well, d’uh. How is that news? Its obviously true and equally obvious entirely irrelevant to establishing a case for believing MMR has a role in causing autism. Its a tactical appeal to emotion – nothing more.

He added that after agreeing to be an expert witness on drug-safety trials for parents’ lawyers, he had received and studied thousands of documents relating to the case which he believed the public had a right to see. He said he has seen a “steady accumulation of evidence” from scientists worldwide that the measles, mumps and rubella jab is causing brain damage in certain children.

This is at the heart of the two articles. Dr Fletcher however simply invokes the spirit of these ‘thousands of documents’ and doesn’t discuss them or what they contain at all. It may well be that he’s hampered by the legal constraints of the case(s) in question but thats really besides the point. What we need to know is – what can Dr Fletcher _add_ to the debate? Both the epidemiology and the hard science have refuted the MMR link on more than one occasion. If Dr Fletcher has peer reviewed journal based evidence that contradicts or invalidates the science done so far then he should state it. At the moment he is simply repeating a fallacy of intuition, magical thinking and an argument to the future. None of these lend any scientific credence to making a case that supports the idea that the MMR jab caused or contributed to anyones autism. If there’s evidence lets get it peer reviewed and published in a respected journal – anything else is simply hearsay.

But he added: “There are very powerful people in positions of great authority in Britain and elsewhere who have staked their reputations and careers on the safety of MMR and they are willing to do almost anything to protect themselves.”

This is a combination of Galileo gambit and a fallacy of the assumed but hidden truth. In other words its the invocation of a conspiracy theory. Its an easy thing to say because one doesn’t have to prove or even allege who these ‘powerful people’ actually are and thus there is no one available to defend the given proposition. I always think of this as the last refuge of the truly desperate. If someones case is strong enough then why resort to such a transparent and desperate tactic?

Clinical and scientific data is steadily accumulating that the live measles virus in MMR can cause brain, gut and immune system damage in a subset of vulnerable children,” he said.

It is? Where? In fact the vast weight of scientific evidence has very recently concluded that there is no link.

There was no credible evidence behind claims of harm from the MMR vaccination. This is the conclusion drawn by the Cochrane Review Authors, an international team of researchers, after carefully drawing together all of the evidence found in 31 high quality studies from around the world. They also highlight that the policy of encouraging mass use of MMR has eliminated the scourge of measles, mumps and rubella from many countries. _”In particular we conclude that all the major unintended events, such as triggering Crohn’s disease or autism, were suspected on the basis of unreliable evidence,”_ says lead author Dr Vittorio Demicheli who works at Servizo Sovrazonale di Epidemiologia, Alessandria, Italy.

By contrast, Dr Fletcher yet again fails to say _what_ this ‘vast weight’ of scientific evidence was, where it could be found and who produced it. He just says its there. And we should just trust him because he’s cleverer than us.

Yet there has been a tenfold increase in autism and related forms of brain damage over the past 15 years, roughly coinciding with MMR’s introduction

Really? Obviously Dr Fletcher (and the Daily Mail) don’t examine the actual science which states:

The new study, which involved 10,903 preschool children in the United Kingdom, confirmed the elevated autism rate, but clearly demonstrated that autism prevalence is not increasing.

Fletcher also makes the mistake of matching correlation with causation – a schoolboy error for any scientist.

He said there was “no way” the tenfold leap in autistic children could be the result of better recognition and definitional changes, as claimed by health authorities.

Another totally specious statement with nothing to back it up. Fletcher might well believe it but as he provides no evidence then its just an opinion. In fact, scientific studies in the US indicate the rise in rate _is_ down to better recognition and diagnosis.

“It is highly likely that at least part of this increase is a vaccine related problem.” he said.

Again, this may be Fletcher’s opinion but he provides nothing in the way of support for it. This isn’t science, this is just gossip.

And thats just about all of Dr Fletcher’s contribution to the debate. Fallacy, lazy reasoning, assertion and unverified claims. It comes as no surprise that other lazy thinkers hype such garbage when they have so little science to support their position.

Drug Error, Not Chelation Therapy, Killed Boy, Expert Says

18 Jan

A report in the Post Gazette includes an interview with Dr. Mary Jean Brown, chief of the Lead Poisoning Prevention Branch of the Atlanta-based Centers for Disease Control and Prevention. She says that:

“without a doubt” that it was medical error, and not the therapy itself, that led to the death of a 5-year-old boy who was receiving it as a treatment for autism.

Which is very interesting on numerous levels.

First (for me) is the statement that clarifies exactly why Tariq was receiving chelation: *”who was receiving it as a treatment for autism”*. That nicely clears up any remaining doubts that Tariq was there for lead poisoning removal. He was there for treatment for autism.

Secondly (and unsurprisingly I take issue with a lot of what Dr Brown claims) is this claim that it was not chelation that killed Tariq. That, to me, is frankly bizarre. Its quite obvious that it is _exactly_ what killed him. If he hadn’t been chelated, he would still be alive. Thats just simple logic. Further, the fact that he was being treated with something that has no proven (or even evidenced) positive effect on ‘recovering’ or ‘curing’ kids from their autism speaks quite clearly to me that it was indeed the chelation that killed him: No autism = no belief in thiomersal poisoning = no chelation = no death. Again, this seems entirely logical to me. EDTA, which is a chelating agent, killed Tariq. QED.

Now, where the ambiguity creeps in is the fact that Dr Brown is claiming that chelation, as a course of action, does not intrinsically harm kids. In fact she said:

She said there have been no reputable medical trials demonstrating the effectiveness of chelation as a therapy for anything but lead poisoning. But if it were administered accurately, the procedure would be harmless.

This is quite a statement. The way I look at it is this: nobody knows the cause of autism. It is likely there are numerous potential triggers. Given that we don’t know what even the chemical composition of the average autistic brain is how can _anyone_ possibly claim that a procedure that removes chemicals is harmless?

And again, I make the point that since chelation has no proven or evidenced positive effect on autism in terms of its removal/curing/recovery/whatever that its use in this case is _directly_ responsible for Tariq’s death.

And there’s more:

“It’s a case of look-alike/sound-alike medications,” she said yesterday. “The child was given Disodium EDTA instead of Calcium Disodium EDTA. The generic names are Versinate and Endrate. They sound alike. They’re clear and colorless and odorless. They were mixed up.”

Mixed up? How can a trained Doctor who ostensibly was a chelationist mix up medications? I guess it could happen but it doesn’t seem likely.

At the end of the day, Dr Brown is offering conjecture. She may have read the autopsy report but her opinion on what Roy Kerry did and why he did it is a matter for an inquiry. At the end of the day a little boy is still dead because he was autistic. Chelation is still responsible for that death.

A Fertile Breeding Ground

11 Dec

I’ve said a few times on here and a few times on other blogs that it is dangerous and irresponsible to maintain an absolutist position on just about anything to do with autism. I can’t remember who said it but whenever I see someone claiming to know for sure what causes autism or what the best course of treatment for autism is I recall a quote that goes something like this:

Follow the man seeking answers, flee from the man who says he knows them all.

However, on occasions I have been known to break this self-imposed belief. This is such an occasion.

Skeptico is a blogger that has commented a few times on various aspects of the thiomersal/mmr/autism ‘connection – notably a thorough debunking of the RFK Salon.com piece earlier this year.

Skeptico mailed me today to draw my attention to a comment made on his site to the effect that the wearing of a tinfoil hat designed to prevent alien abduction can successfully treat autism.

As of Dec. 2005 a hat with velostat worn by autistic children has improved their performance markedly. Michael Menkin is seeking more autistic children in the Seattle, Washington area to try the hat. Some of the autistic children who improved after wearing the hat with velostat for over three months are not related to UFOs or any alien phenomenon.

The researhc of Michael Menkin into alien abductions, with interview of several people with encounter experiences, was featured on KINGTV Evening News Program on November 16, 2005.

This is the sort of shit that one has to wade through to find decent research about autism. Is it on a par with the whole thiomersal/mercury thing? Well yes and no.

No because I can at least see a theoretical connection even if I don’t believe that theory and yes because its another example of a theory driven by anecdotal, unverified, untested belief.

Up until Skeptico mailed me this story, my favourite other crackpot theory was the idea that plastic cups cause autism. Again, this is the sort of mindless crap that detracts from valid science, strips autistic people of the dignity they deserve and only extends ignorance.

Notable in the plastic cup story is the role of one Dr. Stephanie Cave, one of the darlings of the thiomersal/autism connection and listed on page one of the Generation Rescue Hall of Fame. She lent support to a theory that claimed:

…that a toddler became seriously ill and, eventually, “began to exhibit autistic behavior,” after drinking from a plastic spill-proof cup made by Playtex. [Dallas-lawyer Brian R. Arnold ] claims the spill-proof cup was designed in a defective manner that allowed bacteria and mold to build in the cup. Alleging the bacteria caused the child’s condition, Arnold accused Playtex of negligence in distributing a defective cup and demanded $11 million in damages.

Cave claimed that the bacteria and mold caused Dysbiosis, a medical term used pretty much exclusively by the alternative health movement.

She was abetted by William Shaw who owns a laboratory famed amongst thiomersal = autism believers as providing accurate tests for elevated mercury. Shaw said that:

…the child had elevated levels of yeast by-products, indicating a “yeast/fungal overgrowth of the gastrointestinal tract.” Dr. Shaw says such yeast infections cause autism.

Unfortunately for Shaw, it seems that the bacteria found on the plastic cup was not the same sort found on the child in question. Good to know that these labs that so many people claim are accurate obviously double check their work.

Autism is a fertile breeding ground for such hocus-pocus and rubbish because it defies current understanding. That we let this sort of thing grow unchecked is dangerous for the health of children (one wonders if this child went on to be chelated based on such a pack of ineptitude and assumption), dangerous for those of us who wish to find a bit of respect for the state of being autistic and ultimately dangerous to us as a society that we are so willing to let such people treat our children.

This is why we need proper, peer reviewed science performed by those who are proponents of theories and treatments that currently have no efficacy or safety studies. If we continue down this road then treatments like the wearing of a tin foil hat used to prevent autism and alien abduction and causes like a plastic cup will become the norm and our children will truly become lost – not in autism but in the real hell of a frenzied knee-jerk search to treat the increasingly bizarre and to forget about what our _children_ who happen to be autistic need more than anything else. I hope you already know the answer to that. If you don’t then I suggest you step away from the quasi-science.

Andrew Wakefield: Beginning To Regret Libel Case?

6 Nov

There’s new legal paperwork up at Brian Deer’s personal site. It reveals some very interesting facts about two things: First that Andrew Wakefield is instructing his legal team to use his Libel action against Brain Deer as a ‘gagging order’ and secondly that Andrew Wakefield is obviously getting extremely nervous about the effect his GMC hearing will have on his Libel case.

There are three separate actions involving Andrew Wakefield and Brian Deer. One is between Wakefield and the Sunday Times, the other between Wakefield and Brain Deer personally (in respect of his website) and a third one (the one under discussion here) between Wakefield and Channel 4/Twenty twenty Productions.

The ruling judge in this case first said that it was certain that the outcome of just one of these actions would determine the outcome of the others as all three rest on the exact same subject matter. [edit – not sure I got that exactly right – if anyone reads it and comes to a different conclusion, please let me know]

Andrew Wakefield has applied for a ‘stay’ in this case (the C4/2020 one). This means he essentially wants to put this action ‘on hold’. He wants to do this because he claims that the GMC case has seniority over this one. Justice Eady remained distinctly unimpressed with this argument:

In the light of this timescale, it is impossible to envisage the trial of these libel proceedings taking place before the Michaelmas term of 2007. Much of the evidence relating to the issue of justification relates to the mid-90s and a delay of that kind would be plainly undesirable. It would, moreover, involve a gap of three years between the broadcast in question and the trial. That is beyond what is normally regarded as acceptable in the modern climate for the span of a libel action between publication and trial – even in a complicated case…

In British law it is part of the case to consider that a Libel action should be acted on as hastily as possible as the defendant may have good need to clear their name – people like Brian Deer for example who, as an investigative journalist, needs to be trusted to be employable.

So why would Wakefield wish to grant a stay to after the GMC hearing? Because he wants to ‘test the water’ with the GMC action which at most can strip him of his license – a minor inconvenience for one who’s already making a living in Texas – whereas a libel action can strip him of a hell of a lot more. I’m guessing that when things go bad for him and the GMC strip him of his license that all other actions will be quietly dropped.

However, even though he has asking for a stay of this particular action Andrew Wakefield is not above using it as a weapon to browbeat people:

These factors loom even larger in the present case in the light of certain conduct on the Claimant’s part which Miss Page has prayed in aid. It is her case that *the Claimant is seeking to take full advantage of the fact that he has issued libel proceedings while avoiding any detailed public scrutiny of the underlying merits*. In other words, she argues, he is seeking to adopt a strategy comparable to that generally characterised by the phrase “a gagging writ”. It is necessary to consider these allegations in a little further detail.

A few of you may remember that Wakefield took part in their original Power of Parents rally in the US during which he read an extract of a statement in which a small British paper (the Cambridge Evening News) backed down from a report it had made about Wakefield. Obviously the American parents lapped it up to riotous applause. However, what had _actually_ happened is that Wakefield had instructed his legal team to threaten the Cambridge Evening News with an action like that he had over the Sunday Times:

“You should be aware that proceedings in defamation have already been commenced against The Sunday Times in respect of the article published by Mr Brian Deer on 22nd February 2004. Your article has gone even further than the allegation in The Sunday Times which are currently being litigated and allege impropriety on the part of Mr Wakefield to receive money from lawyers to achieve a predetermined outcome.”

Justice Eady took exception to this:

In my view that paragraph was misleading. Mr Browne (Wakefield’s QC) argues that, even if the circumstances had been set out more fully and accurately, it would have made no difference to the outcome. The editor would still have acknowledged that he had got his facts wrong. That may be, but the important point at the moment is that the editor was given a misleading impression. Because of the stay, to which I have referred, the allegations in The Sunday Times were certainly not “currently being litigated”. They were stayed pending the outcome of serious allegations of professional misconduct against the Claimant, to which no reference was made. It thus appears that the Claimant wishes to use the existence of the libel proceedings for public relations purposes, and to deter other critics, while at the same time isolating himself from the “downside” of such litigation, in having to answer a substantial defence of justification.

And there’s more: Dr Evan Harris MP had criticised Wakefield on a radio programme. He also got a letter:

“[Mr Andrew Wakefield] has asked us to inform you that defamation proceedings have been instituted against Mr Brian Deer and The Sunday Times newspaper in relation to articles that have been appeared [sic] and statements that have been made by them which are defamatory of [him]………..Mr Wakefield has drawn our attention to a number of statements made by you in connection with Mr Wakefield and the question of MMR both in newspapers and in BBC broadcast programme……Given … the fact of litigation having been instituted in defamation and the existence of the General Medical Council inquiry we hope you will agree that further comment on Mr Wakefield’s conduct by you or anyone else should be limited until the outcome of those proceedings has been determined. This will avoid Mr Wakefield having to consider further legal proceedings at the present time”.

Justice Eady took a grave view of this too:

I regard that as a threat that libel proceedings will be issued against Dr Harris unless he “limits” any further comment – not in itself objectionable. On the other hand, the threat is backed up by reference to litigation against The Sunday Times and Mr Deer which, by the date of the letter, had already been stayed. The implication is that for rather vague “sub judice” reasons it would not be appropriate to comment until the proceedings have been determined. At that stage none of the libel actions was “active” within the meaning of the schedule to the Contempt of Court Act 1981 and there was accordingly no reason why Dr Harris should not comment further, if he wished to do so, subject always to the constraints of defamation. Again, one sees the same pattern. The Claimant wishes to use the proceedings for tactical or public relations advantage without revealing that they have been put on the back burner.

And, incredibly, Wakefield also instructed his team to go after the Dept. of Health:

“…In the circumstances Mr Wakefield is concerned and surprised to note that your official website on behalf of the Department of Health offers links not only to Mr Deer’s own website, but also the Channel 4 website on the programme. It seems extraordinary to us and wholly wrong that the Government’s official organ should direct website visitors to another site which not only records partisan and hotly disputed opinions on the subject but is also the subject of defamation proceedings. You will appreciate our grave concern that this fact appears to suggest that Government offers this subject matter official weight and authority.”

This letter is intended to provide formal written warning that the links provided to these two websites are allowing the dissemination of defamatory material. Since this is so you are now invited to withdraw the Department of Health link to these two websites forthwith given that this is an inappropriate use of Governmental weight and authority in such a controversial area”.

Just as a side note I find it incredible that anyone should try and go after a website which links to Brian Deer’s. For their further legal presumption I’d like to present a list of sites that link to Brian Deer’s. I await your issue of a writ against Wikipedia and Google with interest.

Anyway, back to Justice Eady:

I am quite satisfied, therefore, that the Claimant wished to extract whatever advantage he could from the existence of the proceedings while not wishing to progress them or to give the Defendants an opportunity of meeting the claims. It seems to me that these are inconsistent positions to adopt. This conduct is a powerful factor to be weighed in the exercise of the court’s discretion in circumstances which are clearly unique.

And indeed so powerful that Justice Eady ruled that:

I have come to the conclusion, bearing all these considerations in mind, that the interests of the administration of justice require that the Channel 4 proceedings should not be stayed pending the outcome of the GMC proceedings. I appreciate that there will be an increased workload for the Claimant’s advisers, but I do not have any reason to suppose that the firm is incapable of absorbing that extra burden. It is, after all, their client who chose to issue these proceedings and to use them, as I have described above, as a weapon in his attempts to close down discussion and debate over an important public issue. (I note that separate teams of counsel are instructed for the GMC proceedings and the defamation claims.)

So far as the website proceedings are concerned, I see no advantage in those continuing in parallel. There is a significant overlap. I am persuaded that this overlap is so significant, in relation to the defamation proceedings (unlike the GMC disciplinary process), that the outcome of the Channel 4 proceedings is likely to be in practical terms determinative of the others. Mr Deer acts in person in the website proceedings, and a very considerable burden would be placed upon his shoulders if he had to progress that litigation in parallel to the other action, in which he has the advantage of legal representation. Indeed, it may well be that there is a whiff of tactics in the Claimant’s change of stance, whereby he wished to have the website proceedings continue – but only provided there was no stay of the Channel 4 litigation. This is borne out by the suggestion that, before the Claimant should serve his reply, Mr Deer should be obliged to serve a defence in the website proceedings. That proposal has all the hallmarks of a tactical ploy to put Mr Deer at a disadvantage. It would have the effect of isolating him. I am not prepared to go along with that.

Its not looking good for Andrew Wakefield. He’s now been exposed as a bully who likes to threaten with what he has no intention of pursuing. He’s also looking like he’s beginning to realise that he has no chance of escaping the GMC hearings unscathed. Hopefully all those who like to bandy around legal action as a threat will see that a hot head often gets regretted when the facts are examined.

MMR, David & Goliath

21 Sep

I came across an article today by F. Edward Yazbak, MD, FAAP. He’s part of the loose coalition of people who support the MMR/Thiomersal/autism association. The article was mainly about how Thiomersal in Europe is displayed with a skull and crossbones. I may tackle that another time but for now I want to take issue with the following introduction:

In the United Kingdom, the issue of MMR remains in the forefront with a David and Goliath scenario unfolding for the last seven years: On one side, the mighty Government, the Prime-Minister personally, the Health authorities, the Press –some of it very ugly- and large useless epidemiological studies and on the other side, Andrew Wakefield with his study of 12 children and a small group of faithful devoted and informed parents.

There is enough scientific evidence to show that both the MMR vaccine and Thimerosal in other vaccines precipitate autistic regression in genetically-predisposed children, not withstanding the opinions of biased “experts,” a misleading IOM special committee report and obviously the CDC.

Red Flags Weekly.

He also links to a more indepth article apparently but I can’t access it from the link provided.

Lets just tackle these statements as someone who _is_ British and lives in the UK.

The MMR issue is not in the forefront of anything. It remains sporadically in the news due to the efforts of Times journalist Brian Deer. Andrew Wakefield by comparison has fled the country and refuses to be interviewed by Deer. There is indeed a ‘small group’ of press and parents but whilst they are faithful and devoted, they are far from informed.

The facts of the matter are that Andrew Wakefield says he has found an autism related bowel disease in some autistic kids. He may well have, gastric issues are a known comorbidity in some people. There is however, _no link to MMR causing this condition_. No science exists that shows a causative link.

And far from there being just ‘large useless epidemiological studies’ to refute Wakefields claims there are actual ‘hard science’ studies that refute his work.

Firstly is the evidence of his _own lab_.

Even as Andrew Wakefield launched his attack on MMR in 1998, at a press conference and in a video, coinciding with a Lancet paper, he knew that his own laboratory had tested his theory: that the ultimate culprit for the children’s autism was measles virus in the vaccine. Royal Free researcher Nick Chadwick, carrying out sophisticated molecular analysis of samples from the children, using methods agreed by Wakefield, found no trace of measles virus.

Brian Deer.

And lately a new study (which will feature in a BBC documentary) shows that:

Scientists at Guy’s Hospital, in London, have been studying a large group of 100 autistic children. They examined their blood samples, looking for traces of the measles virus in their blood and in that of another group of non-autistic children. The samples were analysed in some of Britain’s leading laboratories, using the most sensitive methods available. The scientists found that 99 per cent of the samples did not contain any trace of the measles virus. Crucially, there was no difference between the autistic and non-autistic children

Awares.

Its also worth noting that *all* of the co-authors of the original Lancet paper have rescinded their position leaving Wakefield standing alone. Next year he will face misconduct charges in the UK from the GMC.

Its further worth noting that at the time he began to criticise the MMR and implicate it in autism causation, Wakefield also claimed he had found another, safer way to vaccinate kids which he duly filed a Patent application for. He later denied this on a website and through his solicitors, however Brain Deer unearthed Wakefield’s Patent application for all to see.

F. Edward Yazbak talks of bias. We have a saying in the UK Sir – ‘people who live in glass houses shouldn’t throw stones’.