No, Wakefield’s Autistic Enterocolitis Does Not Exist

2 Sep

Listen to Andrew Wakefield talk for a while and he will tell you his work has been replicated. Usually claiming replicated multiple times and around the world. Since he says it, it gets repeated by his supporters in online discussions.

For those who get dragged into those discussions, here is another paper to reference. This one takes on the idea that there is a bowel disease specific to autism. Wakefield’s “autistic enterocolitis”

People have looked and, guess what, it isn’t there. Yes, autistics get bowel disease. Being autistic doesn’t prevent bowel disease. The fact that some do, indeed, get bowel disease isn’t what Wakefield claimed. He claimed a “new syndrome”.

It doesn’t exist.

Here’s the abstract. The group is reputable and, in fact, has expressed sympathetic views towards Wakefield.

Evaluation of Intestinal Function in Children With Autism and Gastrointestinal Symptoms.

OBJECTIVE:
Alterations in intestinal function, often characterized as a “leaky gut,” have been attributed to children who are on the autism spectrum. Disaccharidase activity, intestinal inflammation, and permeability were analyzed in 61 children with autism and 50 nonautistic individuals with gastrointestinal symptoms.

METHODS:
All patients had duodenal biopsies assayed for lactase, sucrase, maltase, and palatinase activity. Intestinal permeability was evaluated by rhamnose/lactulose test and measured by high-performance liquid chromatography-mass spectrometry. Intestinal inflammation was evaluated by fecal calprotectin and lactoferrin levels using enzyme-linked immunosorbent assay and histology.

RESULTS:
Some children with autism had mild levels of mucosal inflammation on intestinal biopsy. Disaccharidase activity was not different in autistic and nonautistic individuals. Fecal calprotectin and lactoferrin were similar in both groups. Differences between lactulose and rhamnose recovery and lactulose/rhamnose ratio in urine were not statistically different in patients with and without autism.

CONCLUSIONS:
The present study supports the observation that children with autism who have symptoms of gastrointestinal disorders have objective findings similar to children without autism. Neither noninvasive testing nor endoscopic findings identify gastrointestinal pathology specific to autism, but may be of benefit in identifying children with autism who have atypical symptoms.

If you are getting ready to write, “but they might not have seen enough kids to find one with autistic enterocolitis”, according to Wakefield, most of the kids his team tested had his “new syndrome”. If that were true, this team would have found it.

Add this to “MMR causes autism” as one of the failed ideas of Andrew Wakefield. Not that he will ever admit it.


By Matt Carey

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6 Responses to “No, Wakefield’s Autistic Enterocolitis Does Not Exist”

  1. reissd September 2, 2016 at 21:40 #

    Not that this – or any other paper – will stop Andrew Wakefield from making his claims.

    • Sullivan (Matt Carey) September 3, 2016 at 00:09 #

      Wakefield has never been one to respond to facts or evidence.

      His methods involve appealing to emotion and trying to carefully control information.

  2. Science Mom September 3, 2016 at 04:23 #

    Wakefield has been relegated to the saddest rump of disciples (as BD would say). Which, while still a slimy opportunist and parasite, isn’t appearing before congressional hearings, getting audiences with respectable scientists nor given any favourable media coverage.

  3. Judith October 12, 2016 at 18:19 #

    Distinguishing between ASDs and other diagnoses can be challenging because the traits of ASDs often overlap with symptoms of other disorders and the characteristics of ASDs make traditional diagnostic procedures difficult.

    Comorbid conditions

    Anxiety
    Attention-deficit hyperactivity disorder

    Bipolar disorder

    Bowel disease

    Developmental coordination disorder

    Epilepsy

    Fragile X syndrome

    Gender dysphoria
    Intellectual disability

    Neuroinflammation and immune disorders

    Nonverbal learning disorder
    Obsessive-compulsive
    Tourette syndrome
    Sensory problems
    Tuberous sclerosis

    Sleep disorders

    Other mental disorders

  4. Gisel Gonzalez June 4, 2017 at 17:13 #

    I thought I was going to read something about helping a child in pain and instead I’m in a blog of nay sayers and obviously people who don’t have a child who suffers greatly. It’s always these people who feel that they have any authority over is fact fiction. If your’e not in field getting shot at, and or dodging bullets. Please go blog about Gardening and leave the parents and healers to do their job of solving this painful epidemic.

    • Sullivan (Matt Carey) June 20, 2017 at 19:40 #

      Then go to a blog where Wakefield fans spreads lies. They are easy to find.

      Wakefield is scam artist. Plain and simple. You don’t want to face facts, go places where facts are hidden.

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